Mutagenicity assays of leachate from domestic waste landfills in Japan: The establishment of a protocol for measuring mutagenicity levels of leachate
Mutagenicity assays of leachate from domestic waste landfills in Japan: The establishment of a protocol for measuring mutagenicity levels of leachate
复制标题
日本生活垃圾填埋场渗滤液致突变性测定：建立渗滤液致突变性水平测量方案
DOI：
10.1007/bf01688200
复制
发表时间：
1991
影响因子：
2.7
通讯作者：
N. Ishinishi
中科院分区：
文献类型：
--
作者：
M. Omura;T. Inamasu;N. Ishinishi
在现代社会中，工业和家庭废物的产生增加得如此之多，以至于废物处理在许多国家已经成为一个严重的问题，这既表现在难以获得废物处理的地点，又表现在对人类环境系统的有害影响的关注。在日本，可燃废物在焚化炉中燃烧，煤渣与不可燃废物一起埋在垃圾填埋场。这些埋藏的物质被土壤细菌和地下存在的物理化学环境降解。这需要大量的时间。然而，垃圾填埋场的渗滤液在整个降解过程中不断扩散到环境中。众所周知，渗滤液中含有各种各样的化学物质，包括有机和无机的，这是由降解过程产生的。因此，应从环境污染和对人类健康的有害影响的角度来审查沥滤液。为评价垃圾渗滤液的致突变性，作者尝试建立了几种方法。他们制定了一项方案，用于预浓缩沥滤液中的诱变剂，并使用鼠伤寒沙门氏菌/沙门氏菌微粒体系统（艾姆斯试验）检查从日本废物填埋场获得的沥滤液的致突变性。
In modern society, production of industrial and domestic waste is increasing so much that waste disposal has become a serious problem in many countries in terms of both difficulty in obtaining a location for waste disposal and concern for the hazardous effects upon the human-environmental system. In Japan, combustible waste is burned in an incinerator and the cinders are buried in landfills together with incombustible waste. These buried substances are degraded by soil bacteria and the physico-chemical milieu existing underground. This requires a great deal of time. However, leachate from the waste landfill is unceasingly dispersed into the environment throughout the degradation period. It is known that leachate contains various kinds of chemicals both organic and inorganic, resulting from the degradation process. Leachate should therefore be examined from the point of view of both environmental pollution and hazardous effects on human health. In an attempt to evaluate the mutagenicity of leachate, the authors endeavored to establish some methods. They developed a protocol for the preconcentration of mutagens in the leachate and for the examination of the mutagenicity of leachate obtained from waste landfills in Japan using the Salmonella typhimurium/mammalian-microsome system (Ames test).