Fluorinated Nanocarbon Film Electrode Capable of Signal Amplification for Lipopolysaccharide Detection
Fluorinated Nanocarbon Film Electrode Capable of Signal Amplification for Lipopolysaccharide Detection
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DOI：
10.1016/j.electacta.2015.12.100
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发表时间：
2016-04
影响因子：
6.6
通讯作者：
A. Oda;Dai Kato;K. Yoshioka;Mutsuo Tanaka;Tomoyuki Kamata;M. Todokoro;O. Niwa
中科院分区：
文献类型：
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作者：
A. Oda;Dai Kato;K. Yoshioka;Mutsuo Tanaka;Tomoyuki Kamata;M. Todokoro;O. Niwa
我们描述了一个电流放大系统，采用氟化纳米碳（F-纳米碳）膜电极形成的非平衡磁控（UBM）溅射与短CF 4等离子体处理。F-纳米碳膜表现出典型的二茂铁基介体的电化学反应，同时强烈抑制Fe 2+离子的电化学氧化。这种选择性仅通过使用F-纳米碳膜电极提供了二茂铁介体与Fe 2+离子的电流放大，而不受Fe 2+离子的直接氧化电流的干扰。利用该电流放大系统实现了一种性能上级的检测脂多糖的电化学生物传感器。由于超平和疏水表面可能产生非常低的噪声，实现了2 ng mL− 1的检测限和良好的重现性（RSD为4.2%）。
We describe a current amplification system that employs a fluorinated nanocarbon (F-nanocarbon) film electrode formed by unbalanced magnetron (UBM) sputtering with a short CF4plasma treatment. The F-nanocarbon film exhibited the typical electrochemical reaction of a ferrocene-based mediator while strongly suppressing the electrochemical oxidation of Fe2+ions. This selectivity provided the current amplification of ferrocene mediators with Fe2+ions solely by using the F-nanocarbon film electrode without interference from the direct oxidation current of Fe2+ions. The current amplification system was used to realize an electrochemical biosensor with superior performance for detecting lipopolysaccharides. A detection limit of 2 ng mL−1with good reproducibility (RSD of 4.2%) was achieved thanks to the very low noise made by possible by the ultraflat and hydrophobic surface.