RELATIVE MOTION OF THE CONNECTIVE TISSUE IN CARPAL TUNNEL SYNDROME: THE RELATION WITH DISEASE SEVERITY AND CLINICAL OUTCOME
RELATIVE MOTION OF THE CONNECTIVE TISSUE IN CARPAL TUNNEL SYNDROME: THE RELATION WITH DISEASE SEVERITY AND CLINICAL OUTCOME
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DOI：
10.1016/j.ultrasmedbio.2020.05.017
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发表时间：
2020-09-01
影响因子：
2.9
通讯作者：
Amadio, Peter C.
中科院分区：
文献类型：
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作者：
Schrier, Verena J. M. M.;Evers, Stefanie;Amadio, Peter C.
腕管综合征（CTS）患者的正中神经和周围滑膜下结缔组织（SSCT）的偏移减少。本研究旨在确定 SSCT 偏移是否可用于预测手术结果。在基线时对特发性 CTS 患者进行了超声和电诊断测试检查。使用散斑跟踪算法来确定相对于肌腱运动（剪切指数）的 SSCT。方差检验分析用于比较 SSCT 运动与基线疾病严重程度。使用调整后的线性回归来测试与患者报告的结果的关联。总共对 90 名 CTS 患者进行了分析，发现平均剪切指数为 79%（95% 置信区间：76.3%-81.6%）。随着电生理严重程度的增加，CTS 患者的 SSCT 运动较低 (p = 0.0475)。术前 SSCT 运动与症状改善没有显着相关性 (p = 0.268)。总体而言，CTS 患者的 SSCT 运动减少，但与临床严重程度的相关性有限。 (C) 2020 年世界医学与生物学超声联合会。版权所有。
Excursion of the median nerve and the surrounding subsynovial connective tissue (SSCT) is diminished in patients with carpal tunnel syndrome (CTS). This study sought to determine if SSCT excursion could be utilized to predict surgical outcome. Idiopathic CTS patients were reviewed with ultrasound and electrodiagnos-tic tests at baseline. A speckle tracking algorithm was used to determine SSCT relative to tendon motion (shear index). Analysis of variance tests were used to compare SSCT motion with disease severity at baseline. Adjusted linear regressions were used to test the association with patient-reported outcome. A total of 90 CTS patients were analyzed and found to have an average shear index of 79% (95% confidence interval: 76.3%-81.6%). SSCT motion was lower in CTS patients with increasing electrophysiological severity (p = 0.0475). There was no significant association of pre-operative SSCT motion with symptomatic improvement (p = 0.268). Overall, SSCT motion is decreased in CTS patients, but exhibits limited correlation with clinical severity. (C) 2020 World Federation for Ultrasound in Medicine & Biology. All rights reserved.