Diagnosis and Treatment of Lymphocutaneous Sporotrichosis: What Are the Options?
Diagnosis and Treatment of Lymphocutaneous Sporotrichosis: What Are the Options?
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DOI：
10.1007/s12281-013-0140-3
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发表时间：
2013-09-01
影响因子：
1.4
通讯作者：
Vazquez-Gonzalez, Denisse
中科院分区：
文献类型：
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作者：
Bonifaz, Alexandro;Vazquez-Gonzalez, Denisse
淋巴皮肤孢子虫病是最常见的临床形式的皮肤孢子虫病。由一种称为申氏孢子丝菌复合体的二态真菌复合体引起，是一种职业病，尤其存在于热带和亚热带地区，并且在所有大陆都有报道。诊断是通过分离病原体来确定的。治疗淋巴皮肤孢子虫病的选择是伊曲康唑，在发展中国家，碘化钾溶液。一般来说，淋巴皮肤形式被认为是一种轻度良性形式的疾病，大多数病例在大约3-4个月的治疗后反应良好。本文就该病的流行病学、临床特点及淋巴皮肤型的诊断作一综述，并对各种治疗方法的优缺点作一简要分析。
Lymphocutaneous sporotrichosis is the most common clinical form of cutaneous sporotrichosis. Caused by a complex of dimorphic fungi called Sporothrix schenckii complex, it is an occupational disease, present especially in tropical and subtropical areas, and has been reported in all continents. Diagnosis is established by isolation of the causative agent. Therapy of choice for lymphocutaneous sporotrichosis is itraconazole, and in developing countries, potassium iodide solution. In general, the lymphocutaneous form is considered a mild benign form of the disease, and the majority of cases respond well to treatment in about 3-4 months of therapy. In this paper, we have made a general review of the disease, especially of the epidemiology, clinical features and diagnosis of the lymphocutaneous form, as well as a brief analysis of the advantages and disadvantages of diverse treatments.