Genetic correlations between mandibular molar cusp areas in baboons
Genetic correlations between mandibular molar cusp areas in baboons
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DOI：
10.1002/ajpa.20528
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发表时间：
2007-03-01
影响因子：
2.8
通讯作者：
Mahaney, Michael C.
中科院分区：
文献类型：
--
作者：
Hlusko, Leslea J.;Do, Nicholas;Mahaney, Michael C.
灵长类进化研究在很大程度上依赖于牙齿的变异，因为牙齿在有机体如何与环境(动物和植物)和同种生物相互作用方面发挥着重要作用。虽然到目前为止，大多数研究都集中在现存和灭绝的古人类身上，但尖端大小的差异已被证明在灵长类分类群中有所不同。在这里，我们测试了假设假设，即这种变异的很大一部分是由于基因的相加效应。我们对来自西南国家灵长类动物研究中心的圈养狒狒(Papio Hamadryas)家系群体进行了下颌磨牙尖二维(2-D)尺寸变异的定量遗传分析。这些分析表明，牙尖大小的变化是可遗传的，并具有性别二型性。此外，我们还测试了同一牙冠上的牙尖之间、沿牙列的形态同源物之间以及牙尖面积和牙冠颊舌宽度之间的遗传相关性。我们发现，第一磨牙上的六对尖牙中，有四对的遗传相关系数为1，但偏锥-亚锥和内锥-下锥在统计学上与零没有什么不同。第二个和第三个磨牙的遗传相关性较低，尽管偏圆锥体-下圆锥体的相关性同样估计为零，而内圆锥体-原锥的相关性估计为1。这种遗传和非遗传相关的交叉模式并不立即符合已知的发育和/或钙化模式。我们提出了两个解释性假设。Am J Phys Anthropol132：445-454,2007。(C)2006年Wiley-Liss，Inc.
Primate evolutionary studies rely significantly on dental variation given the large role that teeth play in how an organism interacts with its environment (animal and plant) and conspecifics. Variation in cusp size has been shown to vary among primate taxa, although most studies to date focused on extant and extinct hominoids. Here we test the assumed hypothesis that a significant proportion of this variation in baboons is due to the additive effects of genes. We perform quantitative genetic analyses on variation in two-dimensional (2-D) mandibular molar cusp size in a captive pedigreed breeding population of baboons (Papio hamadryas) from the Southwest National Primate Research Center. These analyses show that variation in cusp size is heritable and sexually dimorphic. Additionally, we tested for genetic correlations between cusps on the same crown, between morphological homologues along the tooth row, and between cusp area and crown buccolingual width. We find that four of the six cusp pairs on the first molar have a genetic correlation of one, save for the metaconid-hypoconid and entoconid-hypoconid, which are not statistically different from zero. The second and third molars have lower genetic correlations, although the metaconid-hypoconid correlation is similarly estimated at zero and the entoconid-protoconid correlation is estimated to be one. This cross pattern of genetic and no genetic correlation does not immediately accord with the known pattern of development and/or calcification. We propose two explanative hypotheses. Am J Phys Anthropol 132:445-454, 2007. (c) 2006 Wiley-Liss, Inc.