Comparison of donor site intraoral morbidity after mucosal graft harvesting for urethral reconstruction
Comparison of donor site intraoral morbidity after mucosal graft harvesting for urethral reconstruction
复制标题
DOI：
10.1016/j.urology.2005.04.045
复制
发表时间：
2005-10-01
期刊：
影响因子：
2.1
通讯作者：
Gonzalez, CM
中科院分区：
文献类型：
--
作者：
Jang, TL;Erickson, B;Gonzalez, CM
目标。比较接受尿道置换术的男性从下唇和内颊采集粘膜移植物后的术后口内发病率。方法。 2000年至2004年，40名患者接受了口腔粘膜移植物重建尿道。在 40 名患者中，17 名患者接受了下唇切除术（第 1 组），19 名患者接受了内颊切除术（第 2 组），4 名患者同时切除了两个部位（第 3 组）。我们根据采集部位分析了术后不适程度、神经感觉缺陷、唾液流量、并发症和整体生活质量的差异。使用模拟量表和调查问卷评估结果。结果。在长期随访中，从下唇采集移植物的男性中，出现持续术后不适、神经感觉缺陷和唾液流量变化的男性比例高于从脸颊采集移植物的男性。第 1 组和第 2 组的 19 名男性中分别有 1 名（5.9%）和 5 名（26.3%）出现挛缩。在最后一次随访时，下唇切除患者与内颊切除患者的总体生活质量（通过 0 [高兴] 到 6 [糟糕] 的模拟量表测量）没有显着差异（分别为 1.35 与 0.66，P = 0.079）。结论。持续的术后不适、神经感觉缺陷和唾液流量变化在下唇移植的男性中更为常见。然而，与从内颊采集移植物的男性相比，该组的整体生活质量没有显着差异。从发病率的角度来看，内颊似乎是移植物收获的最佳部位。
Objectives. To compare postoperative intraoral morbidity after mucosal graft harvesting from the lower lip and inner cheek in men undergoing substitution urethroplasty.Methods. From 2000 to 2004, 40 patients underwent oral mucosal graft harvesting for urethral reconstruction. Of the 40 patients, 17 underwent harvest from the lower lip (group 1), 19 from the inner cheek (group 2), and 4 from both sites (group 3). We analyzed the postoperative differences in discomfort levels, neurosensory deficits, salivary flow, complications, and overall quality of life according to harvest site. Outcomes were assessed using analog scales and a questionnaire.Results. At longer term follow-up, the proportion of men With persistent postoperative discomfort, neurosensory deficits, and changes in salivary flow was greater in men whose grafts were harvested from the lower lip than in those whose grafts were harvested from the cheek. Contractures were noted in 1 (5.9%) of 17 and 5 (26.3%) of 19 men in groups 1 and 2, respectively. At the last follow-up visit, overall quality of life (measured by an analog scale of 0 [delighted] to 6 [terrible]) was not significantly different in patients with lower lip versus inner cheek harvest (1.35 versus 0.66, respectively, P = 0.079).Conclusions. Persistent postoperative discomfort, neurosensory deficits, and salivary flow changes were more common in men whose grafts were harvested from the lower lip. However, the overall quality of life in this group was not significantly different compared with men whose grafts were harvested from the inner cheek. From a morbidity standpoint, the inner cheek appears to be the preferable site of graft harvest.