Schizophrenic delusions: the detection of warning signals
Schizophrenic delusions: the detection of warning signals
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DOI：
10.1016/s0920-9964(98)00033-4
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发表时间：
1998-06-22
影响因子：
4.5
通讯作者：
Jorgensen, P
中科院分区：
文献类型：
--
作者：
Jorgensen, P
精神分裂症妄想是治疗的重要目标症状。本研究旨在确定妄想形成的预测因素。两个样本的精神分裂症患者（总n=131）进行了前瞻性检查，每隔一周在6个月的时间。在一个样本（n = 60）妄想形成（n = 27; 45%）与早期症状量表（ESS）的8个单项评分的变化显著相关：睡眠、焦虑、注意力集中、易怒、应对、疲劳、抑郁和混乱。这八个项目构成了警告信号量表（WSS）。在另一个样本（n=71），其中43例（61%）的妄想复发的量表的预测效度进行了测试。大于或等于5分的标准临界值结合了可接受的灵敏度（77%）和特异性（68%）。该量表可被患者接受，临床医生可管理，并且具有高度的预测效度和可靠性。这使得它与普通临床实践中的实施相关。(C)1998 Elsevier Science B. V.保留所有权利。
Schizophrenic delusions are important target symptoms for treatment. This study aims to identify predictors of delusion formation. Two samples of schizophrenic patients (total n=131) are examined prospectively every second week during a period of 6 months. In one sample (n = 60) delusion formation (n = 27; 45%) is correlated significantly with a change in score of eight individual items from the Early Signs Scale (ESS): sleep, anxiety, concentration, irritability, coping, tiredness, depression and confusion. These eight items form the Warning Signals Scale (WSS). The predictive validity of the scale is tested in another sample (n=71), of which 43 patients (61%) have reemergence of delusions. A criterion cut-off score of greater than or equal to 5 points combines an acceptable sensitivity (77%) and specificity (68%). The scale is acceptable to patients, manageable for clinicians, and it has a high degree of predictive validity and reliability. This makes it relevant for implementation in ordinary clinical practice. (C) 1998 Elsevier Science B.V. All rights reserved.