Bsoft: Image processing and molecular modeling for electron microscopy

Bsoft: Image processing and molecular modeling for electron microscopy
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DOI:
10.1016/j.jsb.2006.06.006
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发表时间:
2007-01-01
影响因子:
3
通讯作者:
Belnap, David M.
Belnap, David M.
中科院分区:
生物学3区
文献类型:
--
作者:
Heymann, J. Bernard;Belnap, David M.

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BSOFT是一个编写的软件包,用于电子显微照片的图像处理,重建的解释,分子建模和一般图像处理。该代码被模块化以允许快速测试和部署新的处理算法,同时还提供了足够的基础架构来处理许多文件格式和参数数据。该设计是故意打开的,以通过标准参数文件(当前以星级格式的参数进行基于文本的参数编码)及其支持多个图像和分子格式的支持。它还允许进程的外壳脚本,并允许将子任务分布在多个计算机上以进行处理。 Bsoft自初次发行以来就经历了许多修改和进步[Heymann,J.B.,2001。Bsoft:电子显微镜中的图像和分子处理。 J. struct。生物。 133,156-169]。大部分重点是石油单粒子分析和层析成像,包装中有足够的功能,以支持这些技术所需的大多数操作。关键的图形用户界面是程序bshow,它显示图像,用于许多交互式目的,例如拟合对比度传输函数或选择粒子。 BSOFT还提供了各种操纵原子结构的工具,并完善已知分子结构与重建密度的拟合度。由Elsevier Inc.出版
Bsoft is a software package written for image processing of electron micrographs, interpretation of reconstructions, molecular modeling, and general image processing. The code is modularized to allow for rapid testing and deployment of new processing algorithms, while also providing sufficient infrastructure to deal with many file formats and parametric data. The design is deliberately open to allow interchange of information with other image and Molecular processing software through a standard parameter file (Currently a text-based encoding Of parameters in the STAR Format) and its support of multiple image and molecular formats. It also allows shell scripting of processes and allows subtasks to be distributed across multiple computers for Concurrent processing. Bsoft has undergone many modifications and advancements since its initial release [Heymann, J.B., 2001. Bsoft: image and Molecular processing in electron microscopy. J. StrUCt. Biol. 133, 156-169]. Much of the emphasis is oil single particle analysis and tomography, and sufficient functionality is available in the package to support most needed operations for these techniques. The key graphical user interface is the program bshow, which displays an image and is used for many interactive purposes Such as fitting the contrast transfer function or picking particles. Bsoft also offers various tools to manipulate atomic structures and to refine the fit of a known molecular structure to a density in a reconstruction. Published by Elsevier Inc.