Antianoxic action and active constituents of atractylodis lanceae rhizoma.
Antianoxic action and active constituents of atractylodis lanceae rhizoma.
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DOI：
10.1248/cpb.38.2033
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发表时间：
1990-07
影响因子：
1.7
通讯作者：
J. Yamahara;H. Matsuda;Y. Naitoh;H. Fujimura;Y. Tamai
中科院分区：
文献类型：
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作者：
J. Yamahara;H. Matsuda;Y. Naitoh;H. Fujimura;Y. Tamai
进行筛选试验的目的是从天然产物中鉴定新药，用于 KCN 诱导的小鼠缺氧模型。苍术（Atractylodes lancea DC. var. Chinensis Kitamura）的丙酮提取物在KCN诱导的缺氧模型中具有显着的作用，因此选择该提取物进行进一步研究以鉴定其活性成分。结果表明，β-桉醇是苍术中的活性成分。
The screening test was carried out to identify new drugs from natural products for the KCN-induced anoxia model in mice. Acetone extract of Atractylodis Lanceae Rhizoma (Atractylodes lancea DC. var. Chinensis Kitamura) had a significant effect in the KCN-induced anoxia model and therefore the extract was selected for further study in order to identify the active principles. The result showed that beta-eudesmol was the active component in Atractylodis Lanceae Rhizoma.