Investigation of fiducial marker recognition possibility by water equivalent length in real-time tracking radiotherapy
Investigation of fiducial marker recognition possibility by water equivalent length in real-time tracking radiotherapy
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DOI：
10.1007/s11604-021-01207-4
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发表时间：
2021-10-16
影响因子：
2.1
通讯作者：
Tamaki, Yoshio
中科院分区：
文献类型：
--
作者：
Yasue, Kenji;Fuse, Hiraku;Tamaki, Yoshio
实时肿瘤跟踪放射治疗(RTRT)系统通常使用植入肿瘤附近的基准标记来使用X射线透视来跟踪目标。模板模式匹配用于跟踪，通常用于自动定位基准标记。在肝脏放射治疗中，必须对能够识别基准标记物的人体厚度进行临床评估。本研究的目的是利用SyncTraX FX4获得的临床图像，量化在肝脏立体定向全身放射治疗中根据体厚识别基准标记物的情况。检测基准标记物的识别分数与水当量长度(WEL)、管电流和每个平板探测器的关系。研究了基准标记物与背景的对比度与WEL的关系。当WEL大于25 cm时，平均识别分数小于20。当WEL大于30 cm时，图像识别的成功跟踪概率大多小于0.8。在100 mA和140 mA之间，WEL和管电流的关系没有显著差异，但在所有其他组合中有显著差异(p<；0.05)。为了确保在SBRT期间跟踪基准标志物，如果代表身体厚度的WEL大于25 cm，则应根据WEL来确定X射线透视布置。
Real-time tumor tracking radiotherapy (RTRT) systems typically use fiducial markers implanted near the tumor to track the target using X-ray fluoroscopy. Template pattern matching, used in tracking, is often used to automatically localize the fiducial markers. In radiotherapy of the liver, the thickness of the body that can recognize the fiducial markers must be clinically assessed. The purpose of this study was to quantify the recognition of fiducial markers according to body thickness in stereotactic body radiotherapy of the liver using clinical images obtained using SyncTraX FX4. The recognition scores of fiducial markers were examined in relation to water equivalent length (WEL), tube current, and each flat panel detector. The relationship between the contrast ratio of the fiducial marker and the background and the WEL was also investigated. The average recognition score was found to be less than 20 when the WEL was greater than 25 cm. The probability of successful tracking of image recognition was mostly smaller than 0.8 when the WEL was over 30 cm. The relationship between WEL and tube current did not significantly differ between 100 and 140 mA, but there was a significant difference (p < 0.05) for all other combinations. To ensure tracking of fiducial markers during SBRT, if the WEL representing body thickness is longer than 25 cm, the X-ray fluoroscopy arrangement should be determined based on the WEL.