Saccharomyces cerevisiae TEC1 is required for pseudohyphal growth
Saccharomyces cerevisiae TEC1 is required for pseudohyphal growth
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DOI：
10.1111/j.1365-2958.1996.tb02470.x
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发表时间：
1996-03-01
影响因子：
3.6
通讯作者：
Timberlake, WE
中科院分区：
文献类型：
--
作者：
Gavrias, V;Andrianopoulos, A;Timberlake, WE
不同的真核生物共享具有同源DNA结合结构域的发育转录因子。我们发现发育调节因子AbaA是丝状真菌构巢曲霉（Aspergillusnidulans）的ATTS/TEA（（A）在bar B（a）A下，（T）在bar EF-1下，（T）在bar EC 1下，（T）在bar EF-1下，（T）在bar EC 1下，（A）在bar baA下）类转录因子的成员，诱导酵母酿酒酵母（Saccharomycescerevisiae）中的假菌丝发育。色葡萄AbaA的酿酒酵母同源物TEC 1 p是这种形态转变所必需的。我们提供的证据表明，TEC 1 p的功能与STE 12 p合作，以诱导假菌丝的发展。
Diverse eukaryotic organisms share developmental transcription factors with homologous DNA-binding domains. We showed that the developmental regulator AbaA, a member of the ATTS/TEA ((A) under bar b(a)A, (T) under bar EF-1, (T) under bar EC1, Scalloped/(T) under bar EF-1, (T) under bar EC1, (A) under bar baA) class of transcription factors of the filamentous fungus Aspergillus nidulans, induces pseudohyphal development in the yeast Saccharomyces cerevisiae. The S. cerevisiae homologue of AbaA, TEC1p, is required for this morphological transition. We provide evidence that TEC1p functions in co-operation with STE12p to induce pseudohyphal development.