MIMAS is a new giant multifunctional player in the mitochondrial megacomplex playground

MIMAS is a new giant multifunctional player in the mitochondrial megacomplex playground
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MIMAS 是线粒体巨型复合体游乐场中的新型巨型多功能玩家

DOI:
10.1016/j.celrep.2024.113874
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发表时间:
2024
期刊:
影响因子:
8.8
通讯作者:
Tokatlidis K
Tokatlidis K
中科院分区:
生物学1区
文献类型:
--
作者:
Tokatlidis K

文献摘要

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线粒体富含通常专用于一种功能的多蛋白质组合。在本期《细胞报告》中,Horten等人描述了线粒体内膜上一个3纳米的巨型复合体,它具有整合线粒体生物发生和新陈代谢的多种功能。
Mitochondria are rich in multi-protein assemblies that are usually dedicated to one function. In this issue ofCell Reports,Horten et al.1describe a 3-nanometer megacomplex in the mitochondrial inner membrane, which serves multiple functions integrating mitochondria biogenesis and metabolism.