Diastereoselective synthesis of vicinal amino alcohols
Diastereoselective synthesis of vicinal amino alcohols
复制标题
DOI：
10.1039/c2ob25357g
复制
发表时间：
2012-01-01
影响因子：
3.2
通讯作者：
Koskinen, Ari M. P.
中科院分区：
文献类型：
--
作者：
Karjalainen, Oskari K.;Koskinen, Ari M. P.
邻位氨基醇是天然产物和药物中的常见基序。氨基酸是合成此类功能的天然、廉价且对映体纯的起始材料选择。然而，有关非对映选择性的问题并不明显。本视角着眼于使用各种方法从氨基酸开始非对映选择性合成邻位氨基醇的领域。
The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious. This Perspective takes a look in the field of diastereoselective synthesis of vicinal amino alcohols starting from amino acids using various methods.