SELF-REPORT QUESTIONNAIRE SCORES IN RHEUMATOID-ARTHRITIS COMPARED WITH TRADITIONAL PHYSICAL, RADIOGRAPHIC, AND LABORATORY MEASURES
SELF-REPORT QUESTIONNAIRE SCORES IN RHEUMATOID-ARTHRITIS COMPARED WITH TRADITIONAL PHYSICAL, RADIOGRAPHIC, AND LABORATORY MEASURES
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DOI：
10.7326/0003-4819-110-4-259
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发表时间：
1989-02-15
影响因子：
39.2
通讯作者：
KAYE, JJ
中科院分区：
文献类型：
--
作者：
PINCUS, T;CALLAHAN, LF;KAYE, JJ
研究目的：评估描述类风湿关节炎患者临床状况的简单自我报告问卷的得分是否与传统的身体、放射学、实验室、功能和整体状况的测量相关。设计：在进行自我报告问卷的同时，评估以下变量：美国风湿病协会功能分级、关节计数、手部x线片、红细胞沉降率、类风湿因子滴度、步行时间、握力、按钮测试和整体自我评估。环境：大学风湿病诊所，退伍军人管理局医院的风湿病诊所，以及私人风湿病诊所。患者：该研究包括259名符合美国风湿病协会诊断的明确或典型类风湿性关节炎标准的患者。干预措施：类风湿关节炎患者的标准风湿病治疗。测量结果及主要结果：自述问卷得分与关节计数、x线片评分、红细胞沉降率、握力、钮扣测试、步行时间、美国风湿病协会功能分级、整体自我评价显著相关。将患者分为1.00分，无功能障碍，1.01 ~ 1.50分，1.51 ~ 2.00分，2.01 ~ 3.00分，3.01 ~ 4.00分，进行性功能障碍。在这五类患者中，分别有11%、37%、67%、79%和100%的患者有超过10个受累关节，分别有29%、49%、64%、74%和85%的患者红细胞沉降率大于20mm /h。其他物理和放射测量结果也类似。问卷得分在解释临床状态的其他措施方面与任何其他可用的措施一样有效。结论：简单的自我报告问卷提供的信息与许多类风湿关节炎的传统测量方法相似，似乎是一种有吸引力的、具有成本效益的方法来定量评估和监测个体患者的状态。
Study Objective: To assess whether scores on a simple self-report questionnaire to depict the clinical status of patients with rheumatoid arthritis are correlated with traditional measures of physical, radiographic, laboratory, functional, and global status. Design: The self-report questionnaire was administered at the same time the following variables were assessed: American Rheumatism Association functional class, joint count, hand radiograph, erythrocyte sedimentation rate, rheumatoid factor titer, walking time, grip strength, button test, and global self-assessment. Setting: University rheumatology clinic, the rheumatology clinic of a Veterans Administration hospital, and a private rheumatology practice. Patients: The study included 259 patients who met the criteria of the American Rheumatism Association for a diagnosis of definite or classic rheumatoid arthritis. Interventions: Standard rheumatologic care for patients with rheumatoid arthritis. Measurements and Main Results: Self-report questionnaire scores were significantly correlated with the joint count, radiographic score, erythrocyte sedimentation rate, grip strength, button test, walking time, American Rheumatism Association functional class, and global self-assessment. Patients were categorized into five questionnaire score categories of 1.00, indicating no dysfunction, and 1.01 to 1.50, 1.51 to 2.00, 2.01 to 3.00, and 3.01 to 4.00, indicating progressive dysfunction. In these five categories, more than ten involved joints were seen in 11%, 37%, 67%, 79%, and 100% of patients, respectively, and erythrocyte sedimentation rates greater than 20 mm/h in 29%, 49%, 64%, 74%, and 85% of patients, respectively. Similar results were seen for other physical and radiographic measures. The questionnaire score was as effective in explaining other measures of clinical status as was any other available measure. Conclusions: A simple self-report questionnaire provides information similar to many traditional measures in rheumatoid arthritis and appears to be an attractive, cost-effective approach to assessing and monitoring quantitatively the status of an individual patient.