A ferrochelatase transition-state model. Rapid incorporation of copper(II) into nonplanar dodecaphenylporphyrin
A ferrochelatase transition-state model. Rapid incorporation of copper(II) into nonplanar dodecaphenylporphyrin
复制标题
亚铁螯合酶过渡态模型。
DOI：
10.1021/ic00039a038
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发表时间：
1992
影响因子：
4.6
通讯作者：
Mitsuo Sato
中科院分区：
文献类型：
--
作者：
J. Takeda;T. Ohya;Mitsuo Sato
合成了非平面十二苯基卟啉（H2 DPP），并研究了Cu（II）掺入H2 DPP的动力学.发现H2 DPP的金属化反应速度比平面卟啉四苯基卟啉快6× 105倍。H2DPP反应的另一个显著特征是相对于Cu（II）浓度的饱和动力学，表明形成了中间体
The synthesis of a nonplanar dodecaphenylporphyrin (H 2 DPP) and kinetic studies on Cu(II) incorporation into H 2 DPP are described. The metalation reaction of H 2 DPP was found to be rapid in comparison with that of a planar porphyrin, tetraphenylporphyrin, by a factor of 6×10 5 . Another striking characteristic of the reaction of H 2 DPP is saturation kinetia with respect to the concentration of Cu(II), indicative of the formation of an intermediate