Does Cognition Predict Treatment Response and Remission in Psychotherapy for Late-Life Depression?
Does Cognition Predict Treatment Response and Remission in Psychotherapy for Late-Life Depression?
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DOI:
10.1016/j.jagp.2014.09.003
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发表时间:
2015-02-01
影响因子:
7.2
通讯作者:
Arean, Patricia
中科院分区:
文献类型:
--
作者:
Beaudreau, Sherry A.;Rideaux, Tiffany;Arean, Patricia
To identify cognitive predictors of geriatric depression treatment outcome. Method: Older participants completed baseline measures of memory and executive function, health, and baseline and post-treatment Hamilton Depression Scales (HAM-D) in a 12-week trial comparing psychotherapies (problem-solving vs. supportive; N = 46). We examined cognitive predictors to identify treatment responders (i.e., HAM-Dscores reduced by >= 50%) and remitters (i.e., post-treatment HAM-D score = 82 predicting psychotherapy responders. No other cognitive or health variables predicted psychotherapy outcomes in the decision trees. Conclusions: Psychotherapies that support or improve the executive skill of switching may augment treatment response for older patients exhibiting executive dysfunction in depression. If replicated, Trails B has potential as a brief cognitive tool for clinical decision-making in geriatric depression.