Socioeconomic Status and Neuropsychological Functioning: Associations in an Ethnically Diverse HIV+ Cohort.
Socioeconomic Status and Neuropsychological Functioning: Associations in an Ethnically Diverse HIV+ Cohort.
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DOI：
10.1080/13854046.2015.1029974
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Rivera Mindt M
中科院分区：
文献类型：
--
作者：
Arentoft A;Byrd D;Monzones J;Coulehan K;Fuentes A;Rosario A;Miranda C;Morgello S;Rivera Mindt M
关于社会经济地位（SES）和神经心理功能之间关系的研究有限，特别是在种族/少数民族和艾滋病毒阳性人群中。然而，在美国，贫困、教育、艾滋病毒疾病、种族/民族和健康结果之间存在复杂的联系。我们使用标准化的SES测量（即Hollingshead量表）、综合NP测试组和功能评估（即患者自身功能量表评估和修改的日常生活工具活动量表）在134名不同种族的HIV+成年人样本中探索了这些关系。双变量分析表明，成人SES与语言流畅性、注意力/集中、学习、记忆、处理速度和执行功能等特定测试中的神经心理表现显著正相关，而儿童SES与语言流畅性、处理速度和执行功能的测量显著相关。在一系列的线性回归中，控制SES显著减弱了种族/少数民族个体和非西班牙裔白人个体之间NP测试成绩的群体差异。最后，在hiv相关神经认知障碍（HAND）诊断中，SES评分有显著差异。在二元逻辑回归中，SES是HAND诊断的唯一独立预测因子。由于显著的健康差异，社会经济地位较低的艾滋病毒阳性个体可能更容易受到艾滋病毒相关的神经心理后遗症的影响，尽管这在多大程度上受到测试偏差等因素的影响尚不清楚。总的来说，我们的研究结果表明，SES与HIV+个体的神经心理测试表现显著相关，是临床实践中需要考虑的重要因素。
There is limited research examining the relationship between socioeconomic status (SES) and neuropsychological functioning, particularly in racial/ethnic minority and HIV+ populations. However, there are complex associations between poverty, education, HIV disease, race/ethnicity, and health outcomes in the US. We explored these relationships among an ethnically diverse sample of 134 HIV+ adults using a standardized SES measure (i.e., the Hollingshead scale), a comprehensive NP test battery, and a functional evaluation (i.e., Patient’s Assessment of Own Functioning Inventory and Modified Instrumental Activities of Daily Living Scale). Bivariate analyses showed that adult SES was significantly, positively correlated with neuropsychological performance on specific tests within the domains of verbal fluency, attention/concentration, learning, memory, processing speed, and executive functioning, and childhood SES was significantly linked to measures of verbal fluency, processing speed, and executive functioning. In a series of linear regressions, controlling for SES significantly attenuated group differences in NP test scores between racial/ethnic minority individuals and non-Hispanic white individuals. Finally, SES scores significantly differed across HIV-Associated Neurocognitive Disorder (HAND) diagnoses. In a binary logistic regression, SES was the only independent predictor of HAND diagnosis. HIV+ individuals with lower SES may be more vulnerable to HIV-associated neuropsychological sequelae due to prominent health disparities, although the degree to which this is influenced by factors such as test bias remains unclear. Overall, our results suggest that SES is significantly linked to neuropsychological test performance in HIV+ individuals, and is an important factor to consider in clinical practice.
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DOI：
10.1080/13803390701565225
发表时间：
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影响因子：
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作者：
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