Visual field defects after cerebral lesions from the patient's perspective. Health- and vision-related quality of life assessed by SF-36 and NEI-VFQ

Visual field defects after cerebral lesions from the patient's perspective. Health- and vision-related quality of life assessed by SF-36 and NEI-VFQ
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DOI:
10.1007/s00115-007-2342-9
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发表时间:
2008-02-01
期刊:
影响因子:
1.1
通讯作者:
Sabel, B. A.
Sabel, B. A.
中科院分区:
医学4区
文献类型:
--
作者:
Gall, C.;Mueller, I.;Sabel, B. A.

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背景在视野缺损患者中,健康相关生活质量(hQoL)和视觉相关生活质量(vQoL)的测量是视野检查等临床测量的重要辅助手段。本研究的目的是描述脑梗死、创伤性脑损伤和肿瘤等脑损伤后视野缺损患者的hQoL和vQoL。在视野缺损发生后约2年,对24例患者进行了国家眼科研究所-视觉功能问卷(NEI-VFQ)vQoL和SF-36健康调查hQoL。视野测量采用标准视野计和近阈值视野计法。用Landolt-Ring-Test测量视力。NEI-VFQ评分(而非SF-36评分)不仅低于无疾病组,而且低于非脑损伤所致视力障碍患者。视野缺损的大小和NEI-VFQ分量表之间的等级相关性显着高或适度。与SF-36评分,这些相关性一般较低,最好的中度。NEI-VFQ是脑损伤后视野缺损患者自我报告视力损害的一项有价值的测量。非特异性hQoL的测量不足以反映视野缺损患者的问题。
Background. In patients with visual field defects, measurement of health-related quality of life (hQoL) and vision-related quality of life (vQoL) is an important adjunct to clinical measures such as perimetry. The purpose of this study was to describe hQoL and vQoL of patients with visual field defects after cerebral lesions such as infarction, traumatic brain injury, and tumor.Methods. The National Eye Institute - Visual Function Questionnaire (NEI-VFQ) for vQoL and the SF-36 Health Survey for hQoL were administered to 24 patients about 2 years after occurrence of the visual field defect. Visual fields were measured by standard perimetry and a near-threshold campimetric method. Visual acuity was measured by the Landolt-Ring-Test.Results. The NEI-VFQ scores - but not SF-36 scores - were not only lower than those of a disease-free group but also lower than those of patients with visual impairments not caused by cerebral damage. Rank correlations between the size of the visual field defect and NEI-VFQ subscales were significantly high or modest. With SF-36 scores these correlations were generally low and moderate at best.Conclusion. The NEI-VFQ is a valuable measure of self-reported visual impairment in patients with visual field defects after cerebral lesions. The measurement of unspecific hQoL is not sufficient to reflect the problems of patients with visual field defects.