Prevalence of Pigment Dispersion Syndrome in Patients Seeking Refractive Surgery
Prevalence of Pigment Dispersion Syndrome in Patients Seeking Refractive Surgery
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DOI：
10.1097/ijg.0000000000001193
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发表时间：
2019-05-01
影响因子：
2
通讯作者：
Cauble, Jae E.
中科院分区：
文献类型：
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作者：
Doane, John F.;Rickstrew, Jace J.;Cauble, Jae E.
目的：确定在视力矫正屈光手术患者中色素分散综合征（PDS）的患病率。地点：密苏里州堪萨斯城发现视觉中心。设计：这是一个前瞻性的病例系列。材料与方法：本前瞻性观察性研究共纳入了319例寻求屈光手术的连续患者的637只眼。患者在屈光手术前接受常规眼科检查。PDS由同一位经验丰富的眼科医生通过存在深前房、虹膜后弓、Krukenberg纺锤体和/或存在中周边虹膜透照缺陷进行诊断。PDS的患病率及其相关的眼科和人口统计学特征进行了评估，在这些诊断。结果：637眼中，165眼（25.9%）诊断为PDS。53只（8.3%）患眼和47只（28.5%）诊断为PDS的患眼存在Krukenberg纺锤体。在153只（95%）被诊断为PDS的眼睛和161只（25.2%）的总眼睛中存在透照缺陷。在诊断为PDS的患者中，性别之间的分布相等（男性vs.女性：26 vs. 25.8%; P=0.942）。蓝色眼睛最有可能患有PDS（35.8%的患者）。结论：PDS在寻求屈光手术的患者人群中的患病率可能高于整体的一般人群。这很可能是自我选择的结果，以及近视和PDS之间的高度关联。由于未经治疗的PDS可能会发生不常见的后遗症，因此屈光外科医生应谨慎地意识到这种患病率的增加，并进行全面检查以正确识别病情。
Purpose: To determine the prevalence of pigment dispersion syndrome (PDS) in patients presenting for vision correcting refractive surgery. Setting: Discover Vision Centers, Kansas City, MO. Design: This is a prospective case series. Materials and Methods: A total of 637 eyes of 319 serial patients who presented seeking refractive surgery were included in this prospective, observational study. Patients underwent routine ophthalmologic examination before refractive surgery. PDS was diagnosed by the presence of a deep anterior chamber, posterior bowing of the irides, Krukenberg spindles, and/or presence of mid-peripheral iris transillumination defects by the same experienced ophthalmologist. The prevalence of PDS and its associated ophthalmic and demographic characteristics were evaluated in those diagnosed. Results: Of the 637 eyes, 165 (25.9%) eyes were diagnosed with PDS. Krukenberg spindles were present in 53 (8.3%) of the total eyes and in 47 (28.5%) eyes that were diagnosed with PDS. Transillumination defects were present in 153 (95%) eyes diagnosed with PDS and 161 (25.2%) total eyes. There was equal distribution between sex in those diagnosed with PDS (male vs. female: 26 vs. 25.8%; P=0.942). Blue colored eyes were most likely to have PDS (35.8% of patients). Conclusions: The prevalence of PDS within the population of patients seeking refractive surgery is likely greater than the general population as a whole. This is most likely the result of self-selection and high association between myopia and PDS. Given that not infrequent sequela can occur from untreated PDS, it is prudent that refractive surgeons be aware of this increased prevalence and perform thorough examinations to properly identify the condition.