Evaluation of flavonoids and diverse antioxidant activities of Sonchus arvensis.
Evaluation of flavonoids and diverse antioxidant activities of Sonchus arvensis.
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DOI：
10.1186/1752-153x-6-126
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发表时间：
2012-10-29
影响因子：
--
通讯作者：
Khan RA
中科院分区：
文献类型：
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作者：
Khan RA
Sonchus arvensis是巴基斯坦的一种传统药物，用于治疗各种人类营养不良。在研究中，其不同组分具有清除多种自由基的特点。结果表明，蛇尾草各部位对自由基（DPPH·、ABTS·+、·OH、超氧化物）的清除作用均显著，但甲醇部位的清除作用强于其他部位。DPPH·、ABTS·+、超氧自由基和总抗氧化活性与总黄酮和酚类物质含量呈显著相关。植物化学分析显示，其中含有山奈酚、槲皮素、东方苷、芦丁、金丝桃苷、儿茶素和杨梅素。从目前的数据可以得出结论，蛇蛇不同部位对自由基的清除作用明显，这可能是由于其多酚成分的存在。
Sonchus arvensis is used in the treatment of various human aliments as a traditional medicine in Pakistan. In the study its various fractions are characterized for scavenging of diverse free radicals. Results of the present study revealed that various fractions of Sonchus arvensis significantly scavenged the free radicals (DPPH·, ABTS·+, ·OH, superoxide), however its methanolic fraction is more potent than other fractions. Significant correlation was found between DPPH·, ABTS·+, superoxide radical and total antioxidant activity with total flavonoids and phenolics contents. Phytochmical analysis revealed the presence kaempferol, quercetin, orientin, rutin, hyperoside, catechin and myricetin. From the present data it is concluded that various fractions of Sonchus arvensis significantly scavenged the free radical, which might be due the presence of polyphenolic constituent.