Plasma cell tumors in HIV-positive patients: Report of a case and review of the literature
Plasma cell tumors in HIV-positive patients: Report of a case and review of the literature
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DOI：
10.1080/10428190500054566
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发表时间：
2005-07-01
影响因子：
2.6
通讯作者：
Axiotis, CA
中科院分区：
文献类型：
--
作者：
Salarieh, A;Rao, C;Axiotis, CA
在HIV阳性患者中，浆细胞肿瘤的发病率有所增加。文献中报道的病例表明，浆细胞瘤发生在比普通人群更年轻的年龄组。病理上，许多肿瘤表现为浆母细胞形态。HIV阳性患者的浆细胞肿瘤可能出现在不寻常的部位，进展迅速，累及多个部位，包括软组织和内脏。预后一般较差。这些特征可能与多种因素有关，包括免疫缺陷、致癌病毒和这些患者细胞因子环境的改变。本文报告一例HIV阳性患者的浆细胞肿瘤。
Plasma cell tumors show an increased incidence in HIV-positive patients. The cases reported in the literature suggest that plasma cell tumors occur in a younger age group than that encountered in the general population. Pathologically, many of these tumors show a plasmablastic morphology. Plasma cell tumors in HIV-positive patients may present at unusual sites and progress rapidly to involve multiple sites, including the soft tissues and viscera. The prognosis is generally poor. These features may be related to a combination of factors, including immunodeficiency, oncogenic viruses, and altered cytokine milieu in these patients. A case of plasma cell tumor in an HIV-positive patient is presented.