Feasibility and Efficacy of the Addition of Heart Rate Variability Biofeedback to a Remote Digital Health Intervention for Depression
Feasibility and Efficacy of the Addition of Heart Rate Variability Biofeedback to a Remote Digital Health Intervention for Depression
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DOI：
10.1007/s10484-020-09458-z
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发表时间：
2020-04-03
影响因子：
3
通讯作者：
Forman-Hoffman, Valerie L.
中科院分区：
文献类型：
--
作者：
Economides, Marcos;Lehrer, Paul;Forman-Hoffman, Valerie L.
抑郁症发病率的上升突出表明，需要采取可获得的有效干预措施。这项研究的目的是确定是否增加了治疗抑郁症的治疗成分，心率变异性生物反馈（HRV-B），以我们最初的智能手机为基础，8周数字化干预是可行的，（“增强”）干预更有可能经历抑郁症状的临床显着改善比我们原来的患者，（“标准”）干预。我们使用了一个准实验，非等效（匹配）组设计，以比较增强组（n = 48）的抑郁症状的变化，从标准组（n = 48）的历史结果数据。在25.8个疗程中，强化组的患者平均完成了3.86小时的HRV-B练习，即使在调整了两组之间的人口统计学和参与度差异后，与标准组的参与者相比，强化组的患者更有可能报告干预后抑郁症状评分的临床显著改善。（调整后OR 3.44，95% CI [1.28-9.26]，P = .015）。我们的研究结果表明，将HRV-B添加到基于应用程序的智能手机远程干预抑郁症是可行的，并可能提高治疗效果。
A rise in the prevalence of depression underscores the need for accessible and effective interventions. The objectives of this study were to determine if the addition of a treatment component showing promise in treating depression, heart rate variability-biofeedback (HRV-B), to our original smartphone-based, 8-week digital intervention was feasible and whether patients in the HRV-B ("enhanced") intervention were more likely to experience clinically significant improvements in depressive symptoms than patients in our original ("standard") intervention. We used a quasi-experimental, non-equivalent (matched) groups design to compare changes in symptoms of depression in the enhanced group (n = 48) to historical outcome data from the standard group (n = 48). Patients in the enhanced group completed a total average of 3.86 h of HRV-B practice across 25.8 sessions, and were more likely to report a clinically significant improvement in depressive symptom score post-intervention than participants in the standard group, even after adjusting for differences in demographics and engagement between groups (adjusted OR 3.44, 95% CI [1.28-9.26], P = .015). Our findings suggest that adding HRV-B to an app-based, smartphone-delivered, remote intervention for depression is feasible and may enhance treatment outcomes.