HEMOSTATIC FACTORS IN THE CORONARY-ARTERY RISK DEVELOPMENT IN YOUNG-ADULTS (CARDIA) STUDY
HEMOSTATIC FACTORS IN THE CORONARY-ARTERY RISK DEVELOPMENT IN YOUNG-ADULTS (CARDIA) STUDY
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DOI：
10.1161/01.atv.14.5.686
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发表时间：
1994-05-01
期刊：
影响因子：
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通讯作者：
LIU, K
中科院分区：
文献类型：
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作者：
GREEN, D;RUTH, KJ;LIU, K
据报道，在中老年人群中，因子VII （FVII）和纤维蛋白原（Fb）水平升高是冠心病的危险因素。本研究的目的是确定这些和其他止血因子（FVIII，血管性血友病因子[vWF]）水平的升高是否与参加年轻人冠状动脉风险发展（CARDIA）研究的年轻人的其他冠状动脉危险因素相关。在1724名年龄在23至35岁之间的参与者中测量了止血因子，这些参与者按性别和种族（黑人/白人）大致平衡。女性的血压高于男性(黑人288比253毫克/分升；白人267比240毫克/分升
Elevated levels of factor VII (FVII) and fibrinogen (Fb) have been reported as risk factors for coronary heart disease in middle-aged and older adults. The purpose of this study was to determine whether increased levels of these and other hemostatic factors (FVIII, von Willebrand factor [vWF]) were associated with other coronary risk factors in young adults participating in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Hemostatic factors were measured in 1724 participants aged 23 to 35 years who were roughly balanced by sex and race (black/white). Fb was greater in women than men (black, 288 versus 253 mg/dL; white, 267 versus 240 mg/dL; overall P