A cross sectional study of the respiratory health of workers handling printing toner dust

A cross sectional study of the respiratory health of workers handling printing toner dust
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DOI:
10.1136/oem.2005.020644
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发表时间:
2006-04-01
影响因子:
4.9
通讯作者:
Omae, K
Omae, K
中科院分区:
医学2区
文献类型:
--
作者:
Nakadate, T;Yamano, Y;Omae, K

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背景资料:虽然最近的病例报告表明吸入固体墨粉粉尘可能对呼吸系统产生影响,但这一假设尚未得到流行病学研究的证实。目的:进行一项横断面研究,以评估在工作生活中接触固体墨粉粉尘的职业队列中肺纤维化生物学指标与墨粉粉尘暴露之间的关联。对600名男性碳粉工人和212名对照者进行了主观呼吸症状、肺功能和胸部X线检查。结果:接触墨粉20年以上的受试者呼吸道症状和胸部X线异常的发生率较高,但墨粉粉尘暴露与呼吸系统的生物学反应之间没有一致的关系。结论:在当前控制良好的工作环境中,特别是如果小心处理粉末状墨粉,则不太可能发生与墨粉粉尘暴露相关的呼吸健康恶化。尽管如此,重要的是要收集更多的流行病学证据,碳粉吸入的生物效应,最好是使用纵向研究设计。
Background: Although recent case reports have suggested possible respiratory effects of solid toner dust inhalation, this hypothesis has not been verified by epidemiological studies.Objectives: To conduct a cross sectional study to evaluate the association between the biological indices of lung fibrosis and toner dust exposure in an occupational cohort handling solid toner dust in their work life.Methods: A total of 600 male toner workers and 212 control subjects were surveyed in terms of their subjective respiratory symptoms, pulmonary functions, and chest radiographic findings. In addition to the exposure history, the current working conditions and personal exposure levels to toner dust were also examined.Results: Although subjects handling toner for more than 20 years tended to show a higher prevalence of respiratory symptoms and minimal chest x ray abnormalities, there was no consistent relation between the exposure to toner dust and the biological responses of the respiratory system.Conclusion: Deterioration of respiratory health related to toner dust exposure is less likely to occur in current well controlled work environments, especially if the powdered toner is handled carefully. Nonetheless, it is important to collect further epidemiological evidence on the biological effects of toner dust inhalation, preferably using a longitudinal study design.