TOPOGRAPHY OF PROJECTIONS FROM THE MEDIAL PREFRONTAL CORTEX TO THE AMYGDALA IN THE RAT
TOPOGRAPHY OF PROJECTIONS FROM THE MEDIAL PREFRONTAL CORTEX TO THE AMYGDALA IN THE RAT
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DOI：
10.1016/0361-9230(86)90237-6
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发表时间：
1986-09-01
影响因子：
3.8
通讯作者：
WRIGHT, DJ
中科院分区：
文献类型：
--
作者：
CASSELL, MD;WRIGHT, DJ
用荧光染料逆行运输和辣根过氧化物酶-WGA顺行运输的方法研究了大鼠内侧前额叶皮质向杏仁复合体的投射。腹侧扣带前区、前扣带区、边缘下区、眶内侧区和顶盖带被投射到杏仁复合体。来自预备区的投射是从两侧发出的。内侧眶、前扣带回和前扣带回向基底外侧核发出会聚投射。前区有向后外侧皮质核和杏仁-海马区的额外投射。下缘区不投射到基底外侧核，该区域的皮质-杏仁核投射集中在皮质前核和杏仁前区。前缘区和下缘区都投射到中央、内侧和基底内侧核之间的区域。根据类似的投影，这一区域似乎是杏仁前区的尾部延续。结果表明，“基底外侧缘环路”的前额内侧成分主要分布在前扣带回和前额叶。没有证据支持内侧前额叶杏仁核“内脏前脑”的存在。
The projections from the rat medial prefrontal cortex to the amygdaloid complex were investigated using retrograde transport of fluorescent dyes and anterograde transport of horseradish peroxidase-WGA. The ventral anterior cingulate, prelimbic, infralimbic and medial orbital areas and the taenia tecta were found to project to the amygdaloid complex. The projections from the prelimbic area arose bilaterally. The medial orbital, prelimbic and anterior cingulate areas send convergent projections to the basolateral nucleus. The prelimbic area has additional projections to the posterolateral cortical nucleus and amygdalo-hippocampal area. The infralimbic area does not project to the basolateral nucleus and cortico-amygdaloid projection from this area are focussed on the anterior cortical nucleus and the anterior amygdaloid area. Both prelimbic and infralimbic areas project to an area situated between the central, medial and basomedial nuclei. Based on similar projections, this area appears to be a caudal continuation of the anterior amygdaloid area. The results indicate that the medial prefrontal component of the "basolateral limbic circuit" is restricted to the anterior cingulate and prelimbic areas. No evidence was obtained to support the existence of a medial prefronto-amygdaloid component of the "visceral forebrain".