Carbon dots for real-time colorimetric/fluorescent dual-mode sensing ClO−/GSH
Carbon dots for real-time colorimetric/fluorescent dual-mode sensing ClO−/GSH
复制标题
用于实时比色/荧光双模式传感 ClO·/GSH 的碳点
DOI：
10.1016/j.dyepig.2022.110614
复制
发表时间：
2022
影响因子：
4.5
通讯作者：
Xingguo Chen
中科院分区：
文献类型：
--
作者：
Huiqing Li;Zhenni Wei;Xianwei Zuo;Hongli Chen;Cuiling Ren;Yalei Dong;Xingguo Chen
Hypochlorite (ClO − ) and antioxidants have been reported closely correlated with oxidative stress and related diseases. In recent years, many probes, especially fluorescent and colorimetric probes, have been developed to detect ClO − and antioxidants. It is meaningful to develop probes which can be used to detect them in these two modes. Herein, a novel dual mode carbon dots (DM-CDs) which can rapidly respond to ClO − and antioxidants by both fluorescent and colorimetric mode were synthesized. GSH was chosen as model antioxidants to evaluate its detection performance. The fluorescence of DM-CDs can be quenched by ClO − and then recovered by GSH, so sensitive and accurate detection of ClO − and GSH can be achieved. Meanwhile, the colour variation of this system can be observed by naked eye and detected quantitatively UV–Vis spectra. The excellent analytical performance of DM-CDs together with their good biocompatibility endows them with great feasibility in cell imaging and real-time detection of intracellular ClO − and GSH. • An effective, sensitive, and selective dual mode (colorimetric/fluorescent) sensor was synthesized for ClO ¯ and GSH. • The rapidly respond of DM-CDs to ClO ¯ and antioxidants make it can be used in real-time detection. • The excellent analytical performance of DM-CDs together with their good biocompatibility endows them with great feasibility in cell imaging and real-time detection of intracellular ClO ¯ and GSH.
