Epidemiology of atopic dermatitis: a review
Epidemiology of atopic dermatitis: a review
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DOI：
10.2500/aap.2012.33.3569
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发表时间：
2012-05-01
影响因子：
2.8
通讯作者：
DaVeiga, Sigrid Payne
中科院分区：
文献类型：
--
作者：
DaVeiga, Sigrid Payne
特应性皮炎（AD）是一种常见的皮肤病，具有显著的社会和经济负担。阿尔茨海默病影响成人和儿童，全球患病率为1-20%。AD患病率的流行病学和地理变异性的国际研究分三个阶段进行，第三阶段研究有1,000,000名受试者。在世界不同区域，患病率继续变化，并有所变化。尼日利亚、联合王国和新西兰是发病率最高的地区；在随访数据中，拉丁美洲已成为患病率相对较高的区域。在患病率最高的国家，阿尔茨海默病的患病率似乎已达到20%左右的稳定水平，这表明阿尔茨海默病可能不会持续上升，但可能有有限数量的人易患此病。与患病率增加相关的危险因素包括较高的社会经济地位、较高的家庭教育水平、较小的家庭规模和城市环境。研究表明，食物过敏和对环境过敏原的特应性致敏可能不是这种情况的直接原因，而且这种情况存在非特应性形式。大约60%的患者会得到缓解。通过特应性病程发展为哮喘和变应性鼻炎的患者数量取决于其病情的潜在特征。（Allergy Asthma Proc 33:27 -234, 2012; doi: 10.2500/aap.2012.33.3569）
Atopic dermatitis (AD) is a common skin condition with significant associated social and financial burden. AD affects adults and children with worldwide prevalence rates of 1-20%. International study of epidemiology and geographic variability in prevalence of AD has been conducted in three phases with 1,000,000 subjects in the third phase study. Prevalence continues to vary and has changed in different regions of the world. Nigeria, the United Kingdom and New Zealand had been areas of the highest prevalence; Latin America has emerged as a region of relatively high prevalence in follow up data. The prevalence of AD seems to have reached a plateau around 20% in countries with the highest prevalence, suggesting that AD may not be on a continued rise but that a finite number of individuals may be susceptible to the condition. Risk factors associated with increased prevalence include higher socioeconomic status, higher level of family education, smaller family size and urban environment. Research indicates that food allergy and atopic sensitization to environmental allergens may not be directly causal of the condition and that a non-atopic form of the condition exists. similar to 60% of patients will experience remission. The number of patients who will progress through the atopic march to develop asthma and allergic rhinitis depends on the underlying features of their condition. (Allergy Asthma Proc 33:227-234, 2012; doi: 10.2500/aap.2012.33.3569)