Neural unit activity in the trigeminal complex with interpositus or red nucleus inactivation during classical eyeblink conditioning.

Neural unit activity in the trigeminal complex with interpositus or red nucleus inactivation during classical eyeblink conditioning.
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在经典的眨眼条件反射过程中,三叉神经复合体中的神经单元活动与间质或红核失活。

DOI:
10.1037//0735-7044.110.1.13
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发表时间:
1996
影响因子:
1.9
通讯作者:
Lavond,DG
Lavond,DG
中科院分区:
医学4区
文献类型:
--
作者:
Clark,RE;Lavond,DG

文献摘要

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在经典的条件反射过程中,兔三叉神经复合体中的许多神经元表现出与条件刺激(音调)、非条件刺激(喷气)或条件反应(眨眼)有关的活动。由于这些原因,三叉神经复合体被假设为与条件反射相关的神经元可塑性的脑干部位。在这个实验中,当小脑的红核或间位核被降温暂时失活时,三叉神经中与学习相关的活动(与条件反应相关的单位活动)被取消,但刺激诱发的活动不受降温的影响。这项研究和以前的结果支持这样一种说法,即三叉神经中与学习相关的活动是由红核的代位驱动的。(心理信息数据库记录(C)2023 APA,保留所有权利)
During classical conditioning, many neurons in the trigeminal complex of rabbits exhibit activity that is related to the conditioned stimulus (tone), the unconditioned stimulus (airpuff), or to the conditioned response (eyeblink). For these reasons the trigeminal complex has been hypothesized to be a brainstem locus for the neuronal plasticity associated with conditioning. In this experiment, the learning-related activity (unit activity associated with the conditioned response) in the trigeminal is abolished when either the red nucleus or interpositus nucleus of the cerebellum is temporarily inactivated by cooling, but the stimulus-evoked activity is unaffected by cooling. This study and previous results support the suggestion that the learning-related activity seen in the trigeminal is driven by the interpositus by way of the red nucleus.(PsycInfo Database Record (c) 2023 APA, all rights reserved)