A comparison of viral loads between HIV-1-infected elite suppressors and individuals who receive suppressive highly active antiretroviral therapy

A comparison of viral loads between HIV-1-infected elite suppressors and individuals who receive suppressive highly active antiretroviral therapy
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DOI:
10.1086/588791
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发表时间:
2008-07-01
影响因子:
11.8
通讯作者:
Blankson, Joel N.
Blankson, Joel N.
中科院分区:
医学1区
文献类型:
--
作者:
Dinoso, Jason B.;Kim, Scott Y.;Blankson, Joel N.

文献摘要

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精英抑制者是未经治疗的人类免疫缺陷病毒1型(HIV-1)感染者,其病毒载量< 50拷贝/mL。使用单拷贝检测,我们发现精英抑制者和接受抑制性高效抗逆转录病毒治疗的病毒载量< 1拷贝/mL的患者比例之间没有统计学显著差异。
Elite suppressors are untreated individuals with human immunodeficiency virus type 1 (HIV-1) infection who maintain viral loads < 50 copies/mL. Using a single-copy assay, we show that there is no statistically significant difference between the proportions of elite suppressors and patients receiving suppressive highly active antiretroviral therapy who have viral loads of < 1 copy/mL.