Evaluation of the Effects of Everolimus-Eluting and Paclitaxel-Eluting Stents on Target Lesions With Jailed Side Branches: 2-Year Results From the SPIRIT III Randomized Trial
Evaluation of the Effects of Everolimus-Eluting and Paclitaxel-Eluting Stents on Target Lesions With Jailed Side Branches: 2-Year Results From the SPIRIT III Randomized Trial
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DOI：
10.1002/ccd.22606
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发表时间：
2010-11-01
影响因子：
2.3
通讯作者：
Stone, Gregg
中科院分区：
文献类型：
--
作者：
Applegate, Robert;Hermiller, James;Stone, Gregg
目的：评价具有较薄支架支柱和聚合物的依维莫司洗脱支架（EES）是否可减少围手术期肌坏死和不良结局。背景资料：据报告，TAXUS（R）EXPRESS（2）紫杉醇洗脱支架（PES）的围手术期心肌梗死（MI）发生率高于裸金属EXPRESS（2）（R）支架，因为侧分支受损更频繁，推测可归因于PES上支架/聚合物的厚度。研究方法：在SPIRIT III试验中，我们确定了XIENCE V（R）EES组中的113例患者和TAXUS EXPRESS 2 PES组中的63例患者，这些患者均符合病变伴闭塞侧分支的标准（
Objective: To evaluate whether an everolimus-eluting stent (EES) with thinner stent struts and polymer results in less periprocedural myonecrosis and adverse outcomes. Background: Higher periprocedural myocardial infarction (MI) rates have been reported with the TAXUS (R) EXPRESS(2) paclitaxel-eluting stent (PES) compared to the bare metal EXPRESS(2)(R) stent due to more frequent side branch compromise, presumably attributable to the thickness of the stent/polymer on the PES. Methods: In the SPIRIT III trial, we identified 113 patients in the XIENCE V (R) EES group and 63 patients in the TAXUS EXPRESS2 PES group who met the criteria of having a lesion with a jailed side branch (