Radical cations from nitrone spin-traps: Reaction with water to give OH adducts
Radical cations from nitrone spin-traps: Reaction with water to give OH adducts
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DOI：
10.1039/p29960002631
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发表时间：
1996-12-01
期刊：
影响因子：
--
通讯作者：
Symons, MCR
中科院分区：
文献类型：
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作者：
Bhattacharjee, S;Khan, MN;Symons, MCR
将干燥氟利昂基质 (CFCl3) 中的三种广泛使用的硝酮自旋捕集器的稀溶液在 77 K 下暴露于电离辐射下，产生相应的自由基阳离子，并通过其 EPR 光谱进行表征。熔化时，这些自由基阳离子是稳定的，并且获得了良好的液相 EPR 光谱以及氯离子加合物的光谱。当使用含水溶液时，在 77 K 下检测到相同的阳离子。然而，在熔化时，(OH)-O- 具有各向同性光谱特征。以高产率获得自由基加合物。这些结果是根据使用硝酮自旋陷阱检测 (OH)-O- 进行讨论的。自由基，尤其是在生物系统中。
Exposure of dilute solutions of three widely used nitrone spin-traps in dry Freon matrices (CFCl3) at 77 K to ionising radiation gave corresponding radical cations, characterised by their EPR spectra. On melting, these radical-cations were stable and good liquid-phase EPR spectra were obtained, together with spectra for chloride ion adducts. When solutions containing water were used, the same cations were detected at 77 K. However, on melting, isotropic spectra characteristic of the (OH)-O-. radical adducts were obtained in high yield. These results are discussed in terms of the use of nitrone spin-traps to detect (OH)-O-. radicals, especially in biological systems.