Indium(III) acetate-catalyzed intermolecular radical addition of organic iodides to electron-deficient alkenes.
Indium(III) acetate-catalyzed intermolecular radical addition of organic iodides to electron-deficient alkenes.
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DOI：
10.1021/ol702712d
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发表时间：
2008-01
期刊：
影响因子：
5.2
通讯作者：
Katsukiyo Miura;Mitsuru Tomita;J. Ichikawa;A. Hosomi
中科院分区：
文献类型：
--
作者：
Katsukiyo Miura;Mitsuru Tomita;J. Ichikawa;A. Hosomi
在苯硅烷存在和催化量的醋酸铟（III）存在下，在室温下将有机碘添加到乙醇中的缺电子烯烃中。简单有机碘化物和官能化有机碘化物都适用于该反应。一个合理的反应机制包括氢化物从硅转移到铟形成氢化铟，以及氢化铟介导的自由基链过程。
In the presence of phenylsilane and a catalytic amount of indium(III) acetate, organic iodides added to electron-deficient alkenes in ethanol at room temperature. Both simple and functionalized organic iodides were applicable to this reaction. A plausible reaction mechanism involves the formation of indium hydride species by hydride transfer from silicon to indium and an indium hydride-mediated radical chain process.