Helicobacter pylori: Molecular basis for host recognition and bacterial adherence
Helicobacter pylori: Molecular basis for host recognition and bacterial adherence
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DOI：
10.1016/0966-842x(94)90626-2
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发表时间：
1994-01-01
影响因子：
15.9
通讯作者：
Falk, Per
中科院分区：
文献类型：
--
作者：
Boren, Thomas;Normark, Staffan;Falk, Per
从人胃粘膜中分离出的革兰氏阴性螺旋形微需氧菌仅在十多年前才被发现。从那时起，人们对这种灵长类动物特异性病原体产生了很大兴趣，并认为它是慢性活动性胃炎（综述见参考文献2）以及胃溃疡和十二指肠溃疡（综述见参考文献3）的病原体。最近，H。脓毒杆菌感染也与胃腺癌和粘膜相关淋巴组织的发展有关
H Gram-negative, spiralshaped, microaerophilic bacteria isolated from human gastric mucosa, was discovered only just over a decade ago’. Much interest has focused since then on this primatespecific pathogen, and it has been suggested to be a causative agent of chronic active gastritis (reviewed in Ref. 2), and gastric and duodenal ulcers (reviewed in Ref. 3). More recently, H. pyfori infections have also been associated with the development of gastric adenocarcinoma4,-i and mucosaassociated lymphoid tissue