Improvement in the nutritional status after transcatheter aortic valve implantation
Improvement in the nutritional status after transcatheter aortic valve implantation
复制标题
经导管主动脉瓣植入术后营养状况的改善
DOI：
10.1016/j.jjcc.2021.04.006
复制
发表时间：
2021
影响因子：
2.5
通讯作者：
Murohara Toyoaki
中科院分区：
文献类型：
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作者：
Tobe Akihiro;Tanaka Akihito;Tokuda Yoshiyuki;Akita Sho;Miki Yusuke;Furusawa Kenji;Ishii Hideki;Usui Akihiko;Murohara Toyoaki
研究背景经导管主动脉瓣植入术（TAVI）前患者营养状况差与不良临床结局相关。然而，TAVI后的营养状况的变化尚未完全阐明。MethodsIn this single center retrospective observational study，129例患者的营养状况在基线和6个月后TAVI进行了调查。采用预后营养指数（PNI）和老年营养风险指数（GNRI）评估患者基线和6个月时的营养状况。我们进一步评估了根据基线水平分为低和高的亚组中患者营养状况的变化。结果6个月时的PNI和GNRI值显著优于基线[PNI，基线：44.5（41.0-48.0），6个月：46.0（41.9-48.3），p= 0.02; GNRI，基线：95.3（89.0-100.3），6个月：97.8（91.5-101.4），p= 0.006]。基线营养状态较低的患者6个月时的PNI和GNRI值均显著改善，而基线营养状态较高的患者6个月时的PNI和GNRI值无显著变化[PNI，低;基线：36.8（36.1-39.4），6个月：40.8（39.0-43.4），p= 0.002，高;基线：47.0（43.0-49.5），6个月：46.5（43.5-50.5），p= 0.44和GNRI，低;基线：86.4（81.7-88.7），6个月：88.6（83.4-95.3），p= 0.001，高;基线：99.8（95.3-102.8），6个月：100.7（96.8-103.4），p= 0.34]。结论TAVI术后慢性期患者的营养状况可能有所改善，尤其是那些基线水平较差的患者。
BackgroundA poor nutritional status of patients before transcatheter aortic valve implantation (TAVI) has been reported to be associated with poor clinical outcomes. However, changes in the nutritional status following TAVI have not been fully elucidated.MethodsIn this single-center retrospective observational study, 129 patients whose nutritional status at baseline and 6 months after TAVI were available were investigated. The prognostic nutritional index (PNI) and geriatric nutritional risk index (GNRI) were used to assess the nutritional status of the patients at baseline and at 6 months. We further assessed changes in the nutritional status of patients in the subgroups stratified according to the baseline levels as low and high.ResultsThe PNI and GNRI values at 6 months were significantly better than at baseline [PNI, baseline: 44.5 (41.0–48.0), 6 months: 46.0 (41.9–48.3),p= 0.02; GNRI, baseline: 95.3 (89.0–100.3), 6 months: 97.8 (91.5–101.4),p= 0.006]. Both PNI and GNRI values at 6 months were significantly better in the patients with a low baseline nutritional status, while no significant change was observed in those with high baseline levels [PNI, low; baseline: 36.8 (36.1–39.4), 6 months: 40.8 (39.0–43.4),p= 0.002, high; baseline: 47.0 (43.0–49.5), 6 months: 46.5 (43.5–50.5),p= 0.44 and GNRI, low; baseline: 86.4 (81.7–88.7), 6 months: 88.6 (83.4–95.3),p= 0.001, high; baseline: 99.8 (95.3–102.8), 6 months: 100.7 (96.8–103.4),p= 0.34].ConclusionNutritional status of patients might improve during the chronic phase after TAVI, especially in those with poor baseline levels.