SLEEP LOSS IMPAIRS INSPIRATORY MUSCLE ENDURANCE
SLEEP LOSS IMPAIRS INSPIRATORY MUSCLE ENDURANCE
复制标题
DOI：
10.1164/ajrccm/140.4.907
复制
发表时间：
1989-10-01
期刊：
影响因子：
--
通讯作者：
TANG, YR
中科院分区：
文献类型：
--
作者：
CHEN, HI;TANG, YR
睡眠不足在呼吸系统疾病患者中很常见。为了确定睡眠不足是否会影响呼吸肌功能，我们比较了30名正常男性受试者在正常睡眠后与30小时不眠期后测量的呼吸肌和肺功能。呼吸肌肌力由最大静态吸气压和呼气压估计。吸气肌耐力由压力负荷和持续时间的乘积，即压力-时间指数确定，而受试者在改良的Nickerson-Keens装置上对抗吸气压力负荷呼吸。我们发现，吸气肌耐力从871 . ±. 61至638 .+-.睡眠剥夺后69 cm H2O·cm·min。睡眠丧失后，100秒最大自主通气量也显著降低。然而，呼吸肌力、FEV 1和FVC未发生变化。因此，我们得出结论，吸气肌耐力可能会恶化后，30个睡眠损失。
Sleep loss is common in patients with respiratory disorders. To determine whether sleep loss affects respiratory muscle function, we compared respiratory muscle and pulmonary functions after normal sleep with those measured after a 30-h sleepless period in 30 normal male subjects. The respiratory muscle strength was estimated by the maximal static inspiratory and expiratory pressures. Inspiratory muscle endurance was determined by the product of pressure load and the sustained time, i.e, pressure-time index, while the subject breathed against an inspiratory pressure load on a modified Nickerson-Keens device. We found that inspiratory muscle endurance was decremented from 871 .+-. 61 to 638 .+-. 69 cm H2O.cntdot.min after sleep deprivation. Twelve-second maximal voluntary ventilation was also significantly reduced after sleep loss. Nevertheless, the respiratory muscle strength, FEV1, and FVC were unaltered. We therefore conclude that inspiratory muscle endurance may deteriorate after a 30-sleep loss.