Palladium‐Catalyzed Intermolecular C‐2 Alkenylation of Indoles Using Oxygen as the Oxidant
Palladium‐Catalyzed Intermolecular C‐2 Alkenylation of Indoles Using Oxygen as the Oxidant
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DOI：
10.1002/adsc.201300811
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发表时间：
2014-03
影响因子：
5.4
通讯作者：
Zhao-Lei Yan;Wen-Liang Chen;Ya-Ru Gao;Shuai Mao;Yan-Lei Zhang;Yong-Qiang Wang
中科院分区：
文献类型：
--
作者：
Zhao-Lei Yan;Wen-Liang Chen;Ya-Ru Gao;Shuai Mao;Yan-Lei Zhang;Yong-Qiang Wang
发展了一种普适、高效的钯催化吲哚分子间直接碳二烯基化反应。反应具有完全的区域和立体选择性。所有产物在C-2-位均为E-异构体，未检测到Z-异构体和3-取代产物。
A general and efficient palladium-catalyzed intermolecular direct C-2 alkenylation of indoles using oxygen as the oxidant has been developed. The reaction is of complete regio- and stereoselectivity. All products are E-isomers at the C-2-position with no Z-isomers and 3-substituted products were detected.