LIPID-METABOLISM OF BORRELIA-HERMSI
LIPID-METABOLISM OF BORRELIA-HERMSI
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DOI：
10.1128/iai.20.1.215-220.1978
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发表时间：
1978-01-01
影响因子：
3.1
通讯作者：
JOHNSON, RC
中科院分区：
文献类型：
--
作者：
LIVERMORE, BP;BEY, RF;JOHNSON, RC
利用B合成复合脂质。通过用D-[14 C]葡萄糖或[14 C]棕榈酸标记培养物来研究hermsi在Kelly培养基中生长时的生长。将标记的葡萄糖掺入磷脂酰胆碱、磷脂酰甘油、单半乳糖基甘油二酯、胆固醇基葡萄糖苷和酰化胆固醇基葡萄糖苷中。脂肪酸组成反映了介质，这表明该螺旋体直接将酰基链从其外部环境不变。标记的C在酰基（脂溶性）和水溶性部分之间的分布表明，这2个池之间没有代谢交换。B的关系。赫姆西对其他螺旋体的影响在脂质代谢方面作为一般特征进行了讨论。
The synthesis of complex lipids by B. hermsi while growing in Kelly medium was investigated by labeling cultures with D-[14C]glucose or [14C]palmitic acid. Labeled glucose was incorporated into phosphatidyl choline, phosphatidyl glycerol, monogalactosyl diglyceride, cholesteryl glucoside and acylated cholesteryl glucoside. The fatty acid composition reflected that of the medium, suggesting that this spirochete directly incorporates acyl chains unaltered from its external milieu. The distribution of labeled C between acyl groups (lipid-soluble) and water-soluble moieties indicates that there is no metabolic exchange between these 2 pools. The relationship of B. hermsi to other spirochetes is discussed in terms of lipid metabolism as a generic characteristic.