Stem cell therapy for amyotrophic lateral sclerosis.
Stem cell therapy for amyotrophic lateral sclerosis.
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干细胞治疗肌萎缩侧索硬化症
DOI：
10.1186/s13619-015-0026-7
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发表时间：
2015-01-01
期刊：
影响因子：
--
通讯作者：
Chen, Hong
中科院分区：
文献类型：
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作者：
Mao, Zhijuan;Zhang, Suming;Chen, Hong
肌萎缩侧索硬化症（amyotrophiclateralsclerosis，ALS）是一种以运动神经元缺失为特征的致死性神经退行性疾病。目前，没有有效的疗法可用于治疗ALS，除了阿舒唑，其仅具有有限的临床益处。基于干细胞的治疗作为ALS的潜在新治疗策略已被深入和广泛研究，并已被证明至少在一定程度上是有效的。在这篇文章中，我们将回顾目前的研究状况，使用干细胞治疗ALS的治疗，并讨论最有前途的干细胞治疗ALS。
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the loss of motor neurons. Currently, no effective therapy is available to treat ALS, except for Riluzole, which has only limited clinical benefits. Stem-cell-based therapy has been intensively and extensively studied as a potential novel treatment strategy for ALS and has been shown to be effective, at least to some extent. In this article, we will review the current state of research on the use of stem cell therapy in the treatment of ALS and discuss the most promising stem cells for the treatment of ALS.