Cancer microenvironment and inflammation: role of hyaluronan.

Cancer microenvironment and inflammation: role of hyaluronan.
复制标题

DOI:
10.3389/fimmu.2015.00169
复制
发表时间:
2015
影响因子:
7.3
通讯作者:
Tzanakakis GN
Tzanakakis GN
中科院分区:
医学2区
文献类型:
--
作者:
Nikitovic D;Tzardi M;Berdiaki A;Tsatsakis A;Tzanakakis GN

文献摘要

参考文献

被引文献

相似文献

炎症在癌症发展中的作用早在十九世纪就有描述。大量证据支持各种癌症是由感染和慢性炎症性疾病引发的这一命题,而逃避免疫破坏已被提出为新的“癌症标志”之一。肿瘤微环境的改变与肿瘤介导的炎症密切相关。透明质酸(HA)是一种重要的细胞外基质成分,已被公认为是炎症、血管生成、纤维化和癌症促进过程中的积极参与者。这篇综述讨论了HA和特定的HA结合蛋白如何参与和调节与癌症相关的炎症过程。
The role of inflammation in the development of cancer was described as early as the nineteenth century. Abundant evidence supports the preposition that various cancers are triggered by infection and chronic inflammatory disease whereas, evading immune destruction has been proposed as one of the new “hallmarks of cancer.” Changes of the tumor microenvironment have been closely correlated to cancer-mediated inflammation. Hyaluronan (HA), an important extracellular matrices component, has become recognized as an active participant in inflammatory, angiogenic, fibrotic, and cancer promoting processes. This review discusses how HA and specific HA-binding proteins participate in and regulate cancer-related inflammatory processes.
DOI: 10.1016/j.yexcr.2011.01.026
发表时间: 2011-05-01
影响因子: 3.7
作者:
Bharadwaj, Alamelu G.;Goodrich, Nathaniel P.;McAtee, Caitlin O.;Haferbier, Katie;Oakley, Gregory G.;Wahl, James K., III;Simpson, Melanie A.
通讯作者: Simpson, Melanie A.
DOI: 10.2353/ajpath.2009.080501
发表时间: 2009-03-01
影响因子: 6
作者:
Bharadwaj, Alamelu G.;Kovar, Joy L.;Simpson, Melanie A.
通讯作者: Simpson, Melanie A.
DOI: 10.1038/leu.2010.29
发表时间: 2010-04-01
期刊: LEUKEMIA
影响因子: 11.4
作者:
Giannopoulos, K.;Dmoszynska, A.;Schmitt, M.
通讯作者: Schmitt, M.
DOI: 10.1158/0008-5472.can-13-2469
发表时间: 2014-01-01
期刊: Cancer research
影响因子: 11.2
作者:
Bohrer LR;Chuntova P;Bade LK;Beadnell TC;Leon RP;Brady NJ;Ryu Y;Goldberg JE;Schmechel SC;Koopmeiners JS;McCarthy JB;Schwertfeger KL
通讯作者: Schwertfeger KL
DOI: 10.1038/cddis.2013.364
发表时间: 2013-10-03
影响因子: 9
作者:
通讯作者: --