Cancer microenvironment and inflammation: role of hyaluronan.
Cancer microenvironment and inflammation: role of hyaluronan.
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DOI:
10.3389/fimmu.2015.00169
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发表时间:
2015
影响因子:
7.3
通讯作者:
Tzanakakis GN
中科院分区:
文献类型:
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作者:
Nikitovic D;Tzardi M;Berdiaki A;Tsatsakis A;Tzanakakis GN
The role of inflammation in the development of cancer was described as early as the nineteenth century. Abundant evidence supports the preposition that various cancers are triggered by infection and chronic inflammatory disease whereas, evading immune destruction has been proposed as one of the new “hallmarks of cancer.” Changes of the tumor microenvironment have been closely correlated to cancer-mediated inflammation. Hyaluronan (HA), an important extracellular matrices component, has become recognized as an active participant in inflammatory, angiogenic, fibrotic, and cancer promoting processes. This review discusses how HA and specific HA-binding proteins participate in and regulate cancer-related inflammatory processes.
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影响因子:
3.7
作者:
Bharadwaj, Alamelu G.;Goodrich, Nathaniel P.;McAtee, Caitlin O.;Haferbier, Katie;Oakley, Gregory G.;Wahl, James K., III;Simpson, Melanie A.
通讯作者:
Simpson, Melanie A.
影响因子:
6
作者:
Bharadwaj, Alamelu G.;Kovar, Joy L.;Simpson, Melanie A.
通讯作者:
Simpson, Melanie A.
影响因子:
11.4
作者:
Giannopoulos, K.;Dmoszynska, A.;Schmitt, M.
通讯作者:
Schmitt, M.
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11.2
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Bohrer LR;Chuntova P;Bade LK;Beadnell TC;Leon RP;Brady NJ;Ryu Y;Goldberg JE;Schmechel SC;Koopmeiners JS;McCarthy JB;Schwertfeger KL
通讯作者:
Schwertfeger KL
影响因子:
9
作者:
通讯作者:
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