Failure of a permethrin treatment regime to protect cattle against bluetongue virus
Failure of a permethrin treatment regime to protect cattle against bluetongue virus
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DOI：
10.1603/0022-2585-38.5.760
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发表时间：
2001-09-01
影响因子：
2.1
通讯作者：
Velten, RK
中科院分区：
文献类型：
--
作者：
Mullens, BA;Gerry, AC;Velten, RK
在南加州一家奶牛场的密闭饲养场里，荷斯坦小母牛要么沿着腹中线分别喷洒0.2%二氯苯菊酯(250毫升/头)(两栏)，要么不处理(两栏)。在秋季蓝舌病毒传播高峰期(8月22日至10月29日)，每隔2wk进行一次治疗(n=6个日期)。9月15-18日首次出血时蓝舌病毒抗体血清阴性的动物(治疗围栏106只，对照围栏117只)在2个月后(11月12-13日)再次抽血进行检测。血清转换率没有显著差异：试验组为56%，对照组为48%(P>；0.2)。该地区有许多基本上是毗连的隔离奶牛场和废水池塘，产生了大量的索氏库蚊和琼斯，这是主要的蓝舌病毒媒介。此外，据推测，这些奶牛场提供了大量感染病毒的牛，以感染邻近地区的病媒。在这些严峻的病毒挑战条件下，每隔2周使用一次氯氰菊酯未能减少蓝舌病毒的暴露。
Holstein heifers in a confined feedlot setting on a southern California dairy were either sprayed individually along the ventral midline using 0.2% permethrin (250 ml/animal) (two pens) or were not treated (two pens). Treatments (n = 6 dates) were applied every 2 wk during the peak fall bluetongue virus transmission season (22 August-29 October). Animals seronegative for bluetongue virus antibodies at the initial bleeding on 15-18 September (n = 106 in the treatment pens and n = 117 in the control pens) were bled again for testing 2 mo later (12-13 November). Seroconversion rates were not significantly different: 56% for the treated animals and 48% for the controls (P > 0.2). The area has many essentially contiguous confinement dairies with wastewater ponds that produce large numbers of Culicoides sonorensis Wirth & Jones, the primary bluetongue virus vector. Further, these dairies presumably provided a large reservoir of virus-infected cattle to infect vectors in the immediate area. Under these severe virus challenge conditions, permethrin applied at 2-wk intervals failed to reduce exposure to bluetongue virus.