SITE-SPECIFIC RECOMBINATION IN THE IMMUNE-SYSTEM
SITE-SPECIFIC RECOMBINATION IN THE IMMUNE-SYSTEM
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DOI：
10.1096/fasebj.5.14.1752360
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发表时间：
1991-11-01
期刊：
影响因子：
4.8
通讯作者：
LIEBER, MR
中科院分区：
文献类型：
--
作者：
LIEBER, MR
Site-specific DNA recombination has been identified in a wide variety of biological systems. In vertebrates, however, the only identified use of this genetic device is in the immune system. Here it plays a critical role in generating a diverse repertoire of surface receptors to intercept invading microbes and parasites. The mechanism and orchestration of this reaction are intriguing and are relevant to a broad array of related biological and biomedical issues.
