Meeting report from the joint IARC-NCI international cancer seminar series: a focus on colorectal cancer
Meeting report from the joint IARC-NCI international cancer seminar series: a focus on colorectal cancer
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DOI：
10.1093/annonc/mdz044
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发表时间：
2019-04-01
影响因子：
50.5
通讯作者：
Chanock, S. J.
中科院分区：
文献类型：
--
作者：
Gunter, M. J.;Alhomoud, S.;Chanock, S. J.
尽管我们对结直肠癌的病因、生物学和遗传学以及重要的临床进展有了很大的了解，但它仍然是全球第三常见的癌症，是癌症死亡的第二大原因。根据人口预测，全球结直肠癌负担预计将从2018年的180万新病例增加72%，到2040年超过300万，低收入和中等收入国家预计将大幅增加。在本次会议报告中，我们总结了由国家癌症研究所和国际癌症研究机构领导的联合研讨会的内容，该研讨会的举办是为了总结我们在结直肠癌病因、遗传学、早期发现和治疗方面已经取得的重要成就，并确定有待解决的关键研究问题。
Despite significant progress in our understanding of the etiology, biology and genetics of colorectal cancer, as well as important clinical advances, it remains the third most frequently diagnosed cancer worldwide and is the second leading cause of cancer death. Based on demographic projections, the global burden of colorectal cancer would be expected to rise by 72% from 1.8 million new cases in 2018 to over 3 million in 2040 with substantial increases anticipated in low-and middle-income countries. In this meeting report, we summarize the content of a joint workshop led by the National Cancer Institute and the International Agency for Research on Cancer, which was held to summarize the important achievements that have been made in our understanding of colorectal cancer etiology, genetics, early detection and treatment and to identify key research questions that remain to be addressed.