Radiation-induced Xerostomia: Pathophysiology, Prevention and Treatment

Radiation-induced Xerostomia: Pathophysiology, Prevention and Treatment
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DOI:
10.1016/j.clon.2009.09.002
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发表时间:
2009-12-01
期刊:
影响因子:
3.4
通讯作者:
Nutting, C. M.
Nutting, C. M.
中科院分区:
医学2区
文献类型:
--
作者:
Bhide, S. A.;Miah, A. B.;Nutting, C. M.

文献摘要

被引文献

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辐射引起的口干症在头颈癌患者中非常普遍。因此,幸存者会经历相关的长期毒性,可归类为口干综合征:口干、喉咙痛、味觉改变、蛀牙、音质改变以及咀嚼和吞咽功能受损。我们回顾了已发表的描述和报道口干症的研究,并讨论了在预防和治疗这种常见毒性方面取得的进展。车,美国。(2009)。临床肿瘤学21,737 -744 (C) 2009皇家放射学院。Elsevier Ltd.出版。版权所有。
Radiation-induced xerostomia is highly prevalent among patients treated for head and neck cancers. Consequently, survivors experience associated long-term toxicities that may be grouped as xerostomia syndrome: dry mouth, sore throat, altered taste, dental decay, changes in voice quality and impaired chewing and swallowing function. We present a review of published studies describing and reporting xerostomia and discuss advances made in the prevention and treatment of this common toxicity. Bhicle, S. A. et at. (2009). Clinical Oncology 21, 737-744 (C) 2009 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.