Quality of sexual life of women using the contraceptive vaginal ring in extended cycles: Preliminary report

Quality of sexual life of women using the contraceptive vaginal ring in extended cycles: Preliminary report
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DOI:
10.3109/13625187.2014.914488
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发表时间:
2014-08-01
影响因子:
1.7
通讯作者:
Cianci, Antonio
Cianci, Antonio
中科院分区:
医学4区
文献类型:
--
作者:
Caruso, Salvatore;Cianci, Stefano;Cianci, Antonio

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目的评价长期使用避孕环(CVR)的健康女性性生活质量。方法前瞻性研究52例18~32岁寻求激素避孕的女性。女性服用CVR,每天释放15g乙炔雌二醇(EE)和120g依托诺孕酮(ENG),持续63天,然后是4天的无激素间隔,持续两个这样的延长周期。在基线和第一次(第63-73天)和第二次(126-134天)随访时,分别采用女性性功能指数(FSFI)和简明36(SF-36)问卷调查性行为和生活质量。采用女性性困难量表(FSDs)验证性功能障碍是否对女性造成明显的个人痛苦。结果第1次和第2次随访获得的FSFI和FSDs评分较基线评分有改善(p<0.05)。在第1次随访中,躯体疼痛、一般健康和情感角色的QOL测评均有改善(P<0.05);在第2次随访中,所有变量均有改善(P<0.05)。结论根据这些初步数据,延长周期的CVR可以改善女性的性功能和生活质量。
Objective To evaluate the quality of the sexual life of healthy women who are using a contraceptive vaginal ring (CVR) in extended cycles.Methods Fifty-two women (18 to 32 years old) seeking hormonal contraception were enrolled in this prospective study. Women were to use a CVR releasing daily 15 g of ethinylestradiol (EE) and 120 g of etonogestrel (ENG) for 63 days, followed by a four-day hormone-free interval, for two such extended cycles. At baseline and at the first (day 63-73) and second (day 126-134) follow-ups the Female Sexual Function Index (FSFI) and the Short Form-36 (SF-36) questionnaires were administered to investigate, respectively, sexual behaviour and the quality of life (QoL). The Female Sexual Distress Scale (FSDS) was used to verify whether sexual dysfunction caused significant personal distress to the woman.Results The FSFI and FSDS scores obtained at the first and second follow-up appointments detected an improvement with respect to the baseline score (p < 0.05). QoL measures of body pain, general health and emotional role improved at the first follow-up visit (p < 0.05); at the second one, all variables showed improvement (p < 0.05).Conclusion According to these preliminary data the CVR in extended cycles could improve the sexual function and the QoL of women.