Micronuclear and macronuclear sequences of a Euplotes crassus gene encoding a putative nuclear protein kinase.

Micronuclear and macronuclear sequences of a Euplotes crassus gene encoding a putative nuclear protein kinase.
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编码假定的核蛋白激酶的粗化游标基因的微核和大核序列。

DOI:
10.1111/j.1550-7408.1996.tb05048.x
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发表时间:
1996
期刊:
The Journal of eukaryotic microbiology
影响因子:
--
通讯作者:
Klobutcher,LA
Klobutcher,LA
中科院分区:
--
文献类型:
--
作者:
Hale,CA;Jacobs,ME;Estes,HG;Ghosh,S;Klobutcher,LA

文献摘要

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报告了1.8 kbp大核DNA分子(V3)及其大部分微核对应物的序列。大核V3 DNA分子包含一个开放的阅读框架,被一个单一的内含子中断,而微核拷贝被四个内部消除序列中断,其中一个位于内含子内。大核V3基因的预测蛋白产物是一种471个氨基酸的多肽,与植物和动物物种的一组蛋白丝氨酸/苏氨酸激酶非常相似,其中一些成员似乎参与细胞周期或生长控制。
The sequences of a 1.8‐kbp macronuclear DNA molecule (V3), and the majority of its micronuclear counterpart, are reported. The macronuclearV3DNA molecule contains an open reading frame that is interrupted by a single intron, while the micronuclear copy is interrupted by four internal eliminated sequences, one of which is located within the intron. The predicted protein product of the macronuclearV3gene is a 471‐amino acid polypeptide that is very similar to a group of protein‐serine/threonine kinases from both plant and animal species, some of whose members appear to be involved in cell cycle or growth control.