Ventricular cryosurgery: short-term effects on intramural electrophysiology.
Ventricular cryosurgery: short-term effects on intramural electrophysiology.
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心室冷冻手术：对壁内电生理学的短期影响。
DOI：
10.1016/s0003-4975(10)61589-5
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Cox,JL
中科院分区：
文献类型：
--
作者：
Holman,WL;Ikeshita,M;DouglasJr,JM;Smith,PK;Lofland,GK;Cox,JL
本文研究了低温对局部电生理的急性影响，以期设计一种在应用低温两分钟的时间内定位和监测室壁内低温进展的方法。用多点插入电极记录15只犬左室壁内单极电信号。然后采用心外膜、心内膜和心内膜低温，记录心电图单极峰间波幅(UPPA)的变化。通过记录那些显示UPPA下降到控制值的30%以下的心电图的位置，可以预测最终永久冷冻的位置和深度。这种对接受低温消融的心肌区的电生理监测提供了一种将最终低温限制在期望的位置和深度的方法。这使得可以通过选择性地消融致心律失常的室性心肌而不会对周围的非致心律失常的心肌造成损伤，从而在左心室的特定区域精确放置冷冻治疗室性快速性心律失常。
The acute effects of cryothermia on regional electrophysiology were examined in order to devise a means of localizing and monitoring the intramural progression of ventricular cryolesions during a two-minute period of cryothermia application. Intramural unipolar electrograms were recorded from multipoint plunge electrodes placed in the left ventricle in 15 dogs. Epicardial, intramural, and endocardial applications of cryothermia were then employed, and changes in the unipolar peak-to-peak amplitude (UPPA) of electrograms were recorded. The location and depth of the ultimate permanent cryolesion could be predicted by noting locations of those electrograms demonstrating a decrease in the UPPA to less than 30% of the control values.Such electrophysiological monitoring of the region of myocardium undergoing cryothermic ablation provides a means of limiting the ultimate cryolesion to the desired location and depth within the ventricular wall. This allows precise placement of cryolesions in specific areas of the left ventricle for the treatment of ventricular tachyarrhythmias by selectively ablating arrhythmogenic ventricular myocardium without inducing injury in surrounding nonarrhythmogenic myocardium.
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心内膜切除术：治疗复发性室性心动过速的新手术技术
影响因子：
37.8
作者：
M. Josephson;A. Harken;L. Horowitz
通讯作者：
L. Horowitz
室上性快速心律失常的手术治疗。
DOI：
10.1016/s0039-6109(16)43637-6
发表时间：
1985
期刊：
The Surgical clinics of North America
影响因子：
--
作者：
Smith,PK;Holman,WL;Cox,JL
通讯作者：
Cox,JL
影响因子：
2.8
作者：
HAMMERMEISTER, KE;DEROUEN, TA;DODGE, HT
通讯作者：
DODGE, HT
影响因子：
37.8
作者：
GALLAGHER, JJ;ANDERSON, RW;WALLACE, AG
通讯作者：
WALLACE, AG
DOI：
10.1016/s0022-5223(19)39783-1
发表时间：
1973
期刊：
The Journal of thoracic and cardiovascular surgery
影响因子：
--
作者：
E. Mundth;M. Buckley;R. Desanctis;W. Daggett;W. Austen
通讯作者：
W. Austen