FETAL RESPONSES TO ACOUSTIC STIMULATION DEPEND ON HEART-RATE-VARIABILITY PATTERN, STIMULUS-INTENSITY AND REPETITION
FETAL RESPONSES TO ACOUSTIC STIMULATION DEPEND ON HEART-RATE-VARIABILITY PATTERN, STIMULUS-INTENSITY AND REPETITION
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DOI：
10.1016/0378-3782(86)90061-7
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发表时间：
1986-06-01
影响因子：
2.5
通讯作者：
BUSNEL, MC
中科院分区：
文献类型：
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作者：
LECANUET, JP;GRANIERDEFERRE, C;BUSNEL, MC
胎儿(37-40周DA)连续三次暴露于105dBSPL或110dBSPL的5-S高通(800 Hz)粉红色噪声。刺激是在高或低变异性心率(HR)模式(HV或LV)下进行的，据推测，HV或LV模式分别对应于活跃和安静的睡眠时段。有心脏反应(CR)的胎儿比例总是大于有腿部运动(LM)的比例，但伴随腿部运动的存在总是增加CR的幅度，与HR模式、刺激重复和强度无关。胎儿反应性随刺激重复次数的增加而降低，但LV组较HV组在三个维度(CR比、LM比和CR波幅)的降低更明显，105dB刺激比110dB刺激更明显。更重要的是，刺激参数和HR模式是相互作用的。在HV为110分贝时，CRS的中值幅度和CR的概率在试验中都没有改变，但出现整合的LM的概率降低了。在LV为110分贝时，重复导致了从第二次试验开始的所有三个反应维度的减少。在105dBHV时，Lm迅速下降，在110dBLV时也是如此。因此，HR模式所反映的状态在决定CR的发生和幅度以及LM的发生方面起着重要作用，而LM的发生反过来又会增强CR的幅度。
Fetuses (37-40 wks DA) were exposed to three successive presentations of a 5-s high-pass filtered (800 Hz) pink noise either at 105 dB or at 110 dB SPL. Stimulations were given during high or low variability heart rate (HR) patterns (HV or LV) which presumably correspond mostly to active and quiet sleep episodes, respectively. The proportion of fetuses showing cardiac response (CR) was always greater than the proportion showing leg movement (LM) but the presence of an accompanying leg movement always increased the amplitude of CR, independent of HR pattern, stimulus repetition and intensity. Fetal reactiveness always diminished with stimulus repetition but diminished more on the three examined dimensions (CR ratio, LM ratio and CR amplitude) with LV infants than with HV infants, and more with the 105 dB stimulus than with the 110 dB stimulus. More importantly, stimulus parameters and HR patterns interacted. At 110 dB in HV, neither the median amplitude of the CRs nor the probability of a CR changed over trials but the probability of a concommittant LM decreased. At 110 dB in LV, repetition induced a decrement on all three response dimensions from the second trial onwards. At 105 dB in HV, LM decreased rapidly, as much as at 110 dB in LV. Thus, state as reflected by HR pattern, plays a significant role in determining the occurrence and the amplitude of the CR and the occurrence of a LM which, in turn, will enhance the CR amplitude.