The Aluminyl Anion: A New Generation of Aluminium Nucleophile
The Aluminyl Anion: A New Generation of Aluminium Nucleophile
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铝基阴离子：新一代铝亲核试剂
DOI：
10.1002/ange.202007530
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发表时间：
2020
影响因子：
--
通讯作者：
Hicks J
中科院分区：
文献类型：
--
作者：
Hicks J
三价铝化合物以其作为路易斯酸/亲电子试剂的反应性而闻名，这一特性在许多制药、工业和实验室反应中得到利用。最近，报道了一系列可分离的铝（I）阴离子（“铝基”），它们提供了教科书描述的替代方案：这些试剂表现为铝亲核试剂。这篇小型综述涵盖了迄今为止报道的铝基物质及其相关金属配合物的合成、结构和反应性。已经使用通用方法对每个物种的前沿轨道进行了研究，以便对其电子结构进行同类比较，并采用合理化（有时是前所未有的）反应模式的方法。
Trivalent aluminium compounds are well known for their reactivity as Lewis acids/electrophiles, a feature that is exploited in many pharmaceutical, industrial and laboratory‐based reactions. Recently, a series of isolable aluminium(I) anions (“aluminyls”) have been reported, which offer an alternative to this textbook description: these reagents behave as aluminium nucleophiles. This minireview covers the synthesis, structure and reactivity of aluminyl species reported to date, together with their associated metal complexes. The frontier orbitals of each of these species have been investigated using a common methodology to allow for a like‐for‐like comparison of their electronic structure and a means of rationalising (sometimes unprecedented) patterns of reactivity.