Validation of the European Society of Cardiology pre-test probability model for obstructive coronary artery disease

Validation of the European Society of Cardiology pre-test probability model for obstructive coronary artery disease
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DOI:
10.1093/eurheartj/ehaa755
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发表时间:
2021-04-07
影响因子:
39.3
通讯作者:
Bottcher, Morten
Bottcher, Morten
中科院分区:
医学1区
文献类型:
--
作者:
Winther, Simon;Schmidt, Samuel Emil;Bottcher, Morten

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Aims Estimation of pre-test probability (PTP) of disease in patients with suspected coronary artery disease (CAD) is a common challenge. Due to decreasing prevalence of obstructive CAD in patients referred for diagnostic testing, the European Society of Cardiology suggested a new PTP (2019-ESC-PTP) model. The aim of this study was to validate that model.Methods and results Symptomatic patients referred for coronary computed tomography angiography (CTA) due to suspected CAD in a geographical uptake area of 3.3 million inhabitants were included. The reference standard was a combined endpoint of CTA and invasive coronary angiography (ICA) with obstructive CAD defined at ICA as a >= 50% diameter stenosis or fractional flow reserve