Distribution and ultrastructure of the autonomic nerves in the mouse pancreas
Distribution and ultrastructure of the autonomic nerves in the mouse pancreas
复制标题
小鼠胰腺自主神经的分布及超微结构
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
S. Watanabe
中科院分区：
文献类型：
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作者：
T. Ushiki;S. Watanabe
用扫描电镜、透射电镜和光学显微镜（胆碱酯酶技术）研究了小鼠胰腺的外周神经支配。主要神经束在结缔组织隔内常与动脉走行。它们发出纤细的分支，在动脉和小动脉周围形成丛。当到达毛细血管时，神经纤维离开小动脉并在腺泡间隙形成非常松散的网络。伴随动脉的神经也向胰岛发出分支，并在胰岛周围形成密集的神经丛。在胰管周围还存在一些精细的神经纤维。因此，胰腺内神经形成四个丛：血管周围、导管周围、腺泡周围和胰岛。神经丛是由无髓神经纤维构成的网状结构，由具有静脉曲张的轴突和雪旺细胞组成。胰腺内神经节位于小叶间结缔组织中;神经节通常与胰岛密切相关。
Peripheral innervation of the mouse pancreas was studied by scanning and transmission electron microscopy, as well as by light microscopy (cholinesterase technique). Major nerve bundles usually ran with arteries in the connective tissue septa. They gave off delicate branches that formed plexuses around arteries and arterioles. When reaching the capillaries, nerve fibers left the arterioles and formed very loose networks in the interacinar spaces. The nerves accompanying the arteries also sent off branches toward the islets of Langerhans and formed a dense plexus around the islets. A few delicate nerve fibers were also present around the pancreatic ducts. Thus, the intrapancreatic nerves formed four plexuses: perivascular, periductal, periacinar and peri‐insular. The plexuses were networks of unmyelinated nerve fibers consisting of axons with varicosities and Schwann cells. Intrapancreatic ganglia were found in the interlobular connective tissue; ganglia were often closely associated to islets of Langerhans.